Human erythrocyte ghosts were chemically cross-linked with a family of bifunctional cross-linking reagents, imidoesters. Since the reagents are identical in their chemical structures, except for the number of methylene groups, they differ by that distance between the functional groups. The maximum distance is 4.9 A in dimethyl malonimidate, 6.1 A in dimethyl succinimidate, 8.6 A in dimethyl adi...

Human erythrocyte ghosts were chemically cross-linked with a family of bifunctional cross-linking reagents, imidoesters. Since the reagents are identical in their chemical structures, except for the number of methylene groups, they differ by that distance between the functional groups. The maximum distance is 4.9 A in dimethyl malonimidate, 6.1 A in dimethyl succinimidate, 8.6 A in dimethyl adi...

INTRODUCTION Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. OBJECTIVE The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of endodontic therapy by using intracanal medicaments, calcium hydroxide paste ...

Two experiments were conducted to investigate the chemical and fermentative characteristics of by-product-mixed silages consisting wheat straw (WS), grape pomace (GP), olive mill wastewater (OMWW) cheese whey (CW) at 7, 30 90 days. The silage formulations based on a ratio 60% solids (WS + GP) 40% liquids (CW OMWW), with addition water (W) where necessary achieve liquids. In experiment 1, effect...

C49 ENDOTOXEMIA IN TRANSGENIC MICE WITH ANTIOXIDANT ENZYMES 0. Mlrochni tchenko. U. Palnltkar and M. lnouye Rober t Wood J o h n s o n Med lca l School , Un lvers l ty of M e d l c l n e a n d D e n t i s t r y of New Je rsey , Plscataway, New Jersey, USA Reactive oxygen species (ROS) are known to be important mediators of cellular injury during inflammation, either by causing macromolecular da...

Background: Sustained release delivery system can reduce the dosage frequency and maintain the therapeutic level of drugs for a longer time. Biodegradable, biocompatible and thermosensitive chitosan-beta-glycerophosphate (C-GP) solutions can solidify at body temperature and maintain their physical integrity for a longer duration. OBJECTIVES: To develop a novel delivery system based on the integ...

The aim of this study was to explore an effective method for the repair of cartilage defects using chitosan/glycerophosphate (C/GP) gel- and Matrigel-engineered human bone morphogenetic protein 7 (hBMP7)-expressing chondrocytes. Rabbit chondrocytes were obtained, cultured in vitro and transfected with an adenovirus containing hBMP7 and green fluorescent protein (Ad-hBMP7-GFP). The expression of...

p-glycoprotein (p-gp) is a trans-membrane drug efflux pump. several drugs are p-gp substrates. some drugs may affect the activity of p-gp by inhibiting its function, resulting in significant drug-drug interactions (ddis). it is critical to understand which drugs are inhibitors of p-gp so that adverse ddis can be minimized or avoided. this study investigated the effects of gliclazide, metformin,...