BACKGROUND AND PURPOSE Arterial remodeling may enable atherosclerotic disease without luminal stenosis. We sought to assess the prevalence and characteristics of atherosclerosis in angiographically normal carotid arteries. MATERIALS AND METHODS Forty-six arteries with 0% stenosis by MRA were evaluated with multicontrast carotid MR imaging at 3T. For each artery, the percentage wall volume (wa...

Internal jugular vein (IJV) compression has been shown to reduce axonal injury in pre-clinical traumatic brain injury (TBI) models and clinical concussion studies. However, this novel approach to prophylactically mitigating TBI through venous congestion raises concerns of increasing the propensity for hemorrhage and hemorrhagic propagation. This study aims to test the safety of IJV compression ...

The binding of a hybridoma-derived antibody (designated IPH.134-18-6) to an extract of the adult worn of Schistosoma japonicum has been further characterized. This antibody has immunodiagnostic potential for detection of infection with S. japonicum in the Philippines since the binding of labeled hybridoma antibody to a crude adult worm extract in a solid-phase radioimmunoassay (RIA) is inhibite...

Diffuse alveolar hemorrhage (DAH) is a rare and life-threatening condition characterized by hemoptysis, dyspnoea, alveolar infiltrates on chest radiograph and various degrees of anemia. It may occur either as a primary disease of the lungs or a secondary condition due to cardiac, systemic vascular, collagen or renal diseases. Idiopathic pulmonary hemosiderosis (IPH) is a separate form of DAH of...

Background: Inadvertent perioperative hypothermia (IPH) is a common consequence of anaesthesia, defined as core body temperature <36.0°C.1 Adverse effects include surgical site infection, coagulopathy, pain, altered drug metabolism, and adverse cardiac events.1 Preventing IPH vital part the enhanced recovery after surgery programme (ERAS).2 NICE clinical guideline (CG65) provides recommendation...

Introduction. Intraplaque hemorrhage (IPH) is recognized as a plaque destabilizing factor, due to the myriad proatherosclerotic effects of red blood cells (RBCs) [1]. A high resolution, fatand flow-suppressed, T1-weighted MRI sequence (MRIPH) has been shown to detect IPH due to the T1-shortening effects of methemoglobin. Presence of MRIPH positive signal predicts future ischemic events in both ...

BACKGROUND AND AIMS In a large stroke-free population, we sought to identify cardiovascular risk factors and carotid plaque components associated with carotid plaque burden, lumen volume and stenosis. METHODS The carotid arteries of 1562 stroke-free participants from The Rotterdam Study were imaged on a 1.5-Tesla MRI scanner. Inner and outer wall of the carotid arteries were automatically seg...

Idiopathic pulmonary haemosiderosis (IPH) is a rare condition that usually presents as a triad of haemoptysis, iron deficiency anaemia and pulmonary infiltrates. We report a case of IPH diagnosed in a 7 year old boy who had recurrent hospital admissions with severe chest infections and haemoptysis from his first few months of life. He was found to have microcytic hypochromic anaemia, diffuse in...

In 1898 Banti described a disorder characterized by splenomegaly and hypersplenism, resulting in portal hypertension and anemia in the absence of hematological disease. 1 Banti's syndrome is also known as non-cirrhotic portal hypertension (NCPH) in India and Idiopathic Portal Hypertension (IPH) in Japan. Hepatoportal sclerosis seems to be its counterpart in the United States. 2,3 Banti's syndro...