BACKGROUND The ergogenic effects of analgesic substances suggest that pain perception is an important regulator of work-rate during fatiguing exercise. Recent research has shown that endogenous inhibitory responses, which act to attenuate nociceptive input and reduce perceived pain, can be increased following transcranial direct current stimulation of the hand motor cortex. Using high-definitio...

objective: recent studies on treating obsessive compulsive disorder (ocd) have investigated noninvasive brain stimulation techniques such as transcranial direct current stimulation (tdcs) to improve patients’ impaired emotion and cognition. however, such experiments have yielded mixed results, especially with respect to cognition. this study aimed to investigate whether anodal and cathodal tdcs...

In Brief High-definition transcranial direct current stimulation (HD-tDCS) of brain areas related to pain processing may provide analgesic effects evident in the sensory detection and thresholds. The somatosensory sensitivity was assessed after HD-tDCS targeting primary motor cortex (M1) and/or dorsolateral prefrontal (DLPFC). Eighty-one (40 females) subjects were randomly assigned 1 4 anodal p...

Anodal transcranial direct current stimulation (a-tDCS) of primary somatosensory cortex (S1) has been shown to enhance tactile spatial acuity, but there is little information as to the underlying neuronal mechanisms. We examined vibrotactile perception on the distal phalanx of the middle finger before, during, and after contralateral S1 tDCS [a-, cathodal (c)-, and sham (s)-tDCS]. The experimen...

OBJECTIVE We propose the use of a new montage for transcranial direct current stimulation (tDCS), called concentric electrodes tDCS (CE-tDCS), involving two concentric round electrodes that may improve stimulation focality. METHODS To test efficacy and focality of CE-tDCS, we modelled the current distribution and tested physiological effects on cortical excitability. Motor evoked potentials (...

Transcranial direct current stimulation (tDCS) has been used as a useful interventional brain stimulation technique to improve unilateral upper-limb motor function in healthy humans, as well as in stroke patients. Although tDCS applications are supposed to modify the interhemispheric balance between the motor cortices, the tDCS after-effects on interhemispheric interactions are still poorly und...