Selective autophagy and related mechanisms can act as variable defense mechanisms against pathogens and can therefore be considered as intracellular immune responses. When in hepatocytes, Plasmodium parasites reside in a parasitophorous vacuole (PV) and the PV membrane (PVM) is the main contact site between host cell and parasite. Early in infection, the PVM is directly labeled with host cell a...

Infection of mice with pneumonia virus of mice (PVM) is used as a natural host experimental model for studying the pathogenesis of infection with the closely related human respiratory syncytial virus. We analyzed the contribution of T cells to virus control and pathology after PVM infection. Control of a sublethal infection with PVM strain 15 in C57BL/6 mice was accompanied by a 100-fold increa...

This paper describes the architecture and implementation of an integrated message-passing environment consisting of Zipcode and PVM. Zipcode is a highlevel message-passing system for multicomputers and homogeneous networks of computers. PVM is a relatively low-level message-passing system designed for multicomputers and heterogeneous networks of computers. Although PVM provides a workable and e...

In this paper we focus on coordination for parallel systems controlled by the PVM software package. We describe several extensions which allow the use of extended coordination features in PVM. The extensions are designed to support coordination metaphors like gener-ative communication or client server programming. They t into the general philosophy of PVM by adopting an approach to coordination...

More than 75% of a random sample of adult human sera exhibited moderate to high murine pneumonia virus (PVM)-neutralizing activity. There was no correlation between PVM-neutralizing activity and respiratory syncytial virus or parainfluenza type 3 virus-neutralizing activities of the same sera. In children the proportion of sera with moderate to high titres increased with age, indicating early e...

LPVM (Lightweight-process PVM) system is an experimental PVM version which supports the use of lightweight-process or threads as the basic unit of parallelism. It was designed to study potential performance improvements and implementation issues required by multithreaded message-passing systems. The current version of LPVM was implemented on SMPs using the native threads and is designed to be t...

Concurrent computing environments based on loosely coupled networks have proven effective as resources for multiprocessing. Experiences with and enhancements to PVM (Parallel Virtual Machine) are described in this paper. PVM is a software system that allows the utilization of a heterogeneous network of parallel and serial computers as a single computational resource. This report also describes ...

PVM and MPI have often been compared regarding their functionality and performance from the users' point of view. In this paper , however, we will present some comparison from a tool developer's point of view. We will show how a supporting infrastructure { the OMIS compliant monitoring system OCM { can be implemented for both PVM and MPI. Thus, we will put light onto those features of PVM and M...

The Parallel Virtual Machine (PVM) message passing system developed at Oak Ridge National Laboratories has gained widespread acceptance and usage in the parallel programming community. This paper describes the results of performance tests of PVM in a switched FDDI heterogeneous distributed computing environment. We aim to provide insight into how parallel programs, particularly those employing ...