Gastric B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) develops in the chronically inflamed mucosa of patients infected with the bacterial pathogen Helicobacter pylori. Here we use patient material, primary gastric lymphoma cell cultures, and a preclinical model of the disease to examine the role of microRNA (miRNA)-mediated posttranscriptional regulation--focusing in part...

Both 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203; NSC 703786) and 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610; NSC 721648) are antitumor agents with novel mechanism(s). Previous studies have indicated that cytochrome (CYP) P450 1A1 is crucial for 5F-203 activity. In the present study, we investigated the functional role of 2 newly identified CYP P450 enzymes, CYP2S1 and C...

Results Between 2009 and 2010, Multiplex PCR / RT-PCR detected respiratory viruses in 111 (54.7%) of 203 samples. Single virus was detected in 44.8% (91/203) and virus co-infections were observed in 9.9% (20/203). Rhinovirus (40.5%), human Respiratory Syncytial virus (hRSV; 27.9%), and Influenza A virus (9.0%) were the most frequently detected viruses. Adenovirus and human Metapneumovirus were ...

To characterize the Erysipelothrix rhusiopathiae Met-203 type surface protective antigen (Spa) A strains causing swine erysipelas in Japan, the nucleotide sequence of the hypervariable region of the spaA gene was determined in 80 E. rhusiopathiae (serotype 1a) isolates collected from pigs with chronic and subacute swine erysipelas in 14 prefectures in 2008-2014. In this study, 14 (17.5%) isolat...

A number of gastrointestinal parasites have been reported to infect dogs in Nigeria, some which zoonotic potential. Of these, hookworms are the most prevalent, with both Ancylostoma caninum and Uncinaria stenocephala country. In this study, we subjected 203 hookworm microscopy-positive samples 885 individual faecal collected from Nigeria a recently developed multiplex qPCR for detection charact...

Abstract Study question: What is the optimal work-up to establish diagnosis of unexplained infertility, based on best available evidence in literature? Summary answer: The ESHRE Guideline Unexplained Infertility provides 35 recommendations infertility. known already? infertility made when no abnormalities female and/or male reproductive systems are clearly identified. UI inevitably a by exclusi...