Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) are the most frequent skin cancers in humans. An intact immune system is critical for protection against SCC since organ transplant recipients (OTR) have a 60- to 100-fold higher risk for developing these tumors. The role of the innate immune system in tumor immunosurveillance is unclear. Our aim was to determine the expression of sel...

aspects of cancer management including early detection or diagnostic confirmation of cancers, predicting prognosis and/ or response of specific treatment, and disease monitoring after primary treatment. Because the most of tumor markers have showed variable sensitivity and specificity in various conditions of specific cancers, there has been no ideal tumor marker in current clinical practice in...

Value numbering is an optimization that assigns numbers to values in such a way that two values are assigned the same number if and only if the compiler can prove they are equal. When this optimization discovers two computations that produce the same value, it can (under certain circumstances) eliminate one of them. There are two competing techniques for proving equivalences: hashing and partit...

BACKGROUND Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with poor overall survival. New therapeutic strategies that target specific molecular lesions driving advanced disease are needed. Herein we demonstrate the utility of the chicken chorioallantoic membrane (CAM) assay for in vivo human HNSCC tumor growth and metastasis and the tumor suppressive effects of a new chem...

The most common malignancy to involve the oral cavity and oropharynx is squamous cell carcinoma (SCC). Because these oral cancers share an origin from the squamous epithelium, the pathology of oral SCC might be expected to be uniform and its diagnosis repetitive. In reality, the morphologic diversity in SCC, along with the propensity for reactive processes of the oral cavity to mimic SCC histol...