Multidrug-resistant strains of Staphylococcus aureus continue to increase in frequency worldwide, both in hospitals and in the community, raising serious problems for the chemotherapy of staphylococcal disease. Ceftobiprole (BPR; BAL9141), the active constituent of the prodrug ceftobiprole medocaril (BAL5788), is a new cephalosporin which was already shown to have powerful activity against a nu...

The research investigates synthesized Nano-structured PbO2 using ball milling. The structure and morphology of the samples were determined in the process of milling by means of XRD and SEM. The size of particles was estimated through DLS analysis. The TEM image of the synthesized powder verifies the achievement of Nano dimensions. Design and analyses of the results using Taguchi methodology rev...

Business process re-engineering (BPR) has been associated with runaway costs and corporate downsizing. This and other negative connotations have created or strengthened suspicions about the organizational impacts of information technology (IT). This paper considers the fundamental ideas of BPR, with IT as an enabling agent, and examines their consistency with sound management practice. © 1997 E...

This paper proposes the use of Business Process Re-engineering (BPR) methods and analysis tools to address the issues arising in the implementation of electronic voting. We consider the electoral process as one which has to be re-designed in order to effectively accommodate e-Voting technology. We identify the key areas of e-Voting where the use of BPR can provide beneficial results.

a r t i c l e i n f o We extend current research examining synergies between information technology, process redesign, and firm performance in three ways: analyze a firm's entire IT and BPR portfolio, examine production and market value performance implications, and conduct analysis using a unique dataset of 228 firms between 1996 and 1999. We find a contingent association between IT, process r...

It is generally recognized that an organization's information technology (IT) infrastructure can facilitate organizational change, particularly when the information needs of the business process are clearly defined and the capabilities of the IT infrastructure fully explored. Unfortunately, firms engaged in business process redesign (BPR) often struggle to meet these two conditions as outmoded ...

The Biocidal Products Regulation (BPR) contains several provisions for nanomaterials (NMs) and is the first regulation in the European Union to require specific testing and risk assessment for the NM form of a biocidal substance as a part of the information requirements. Ecotoxicological data are one of the pillars of the information requirements in the BPR, but there are currently no standard ...

This research investigates the current status of business process reengineering (BPR) in China by answering the following two questions: How do Chinese business executives view benefits, critical success factors, and major obstacles of BPR implementation? What are the managerial implications of BPR in China? Data were collected by means of survey questionnaires to senior managers in Beijing and...

Although a number of methodologies exist for business process re-design (BPR), supply chain re-design (SCR), and e-business process design, there is a lack of an integrated BPR methodological framework to support supply chain integration (SCI). This paper proposes a detailed framework based on integrating a number of different methodological strands from the literature. A literature review was ...

Business process reengineering (BPR) is a popular management approach, which enables organizations to conduct substantial business and technological improvements. Successful implementation of BPR can assist organizations to change their old-fashioned practices into innovative processes through reorganizing and eliminating some processes and/or finding innovative ways to conduct business activit...