نتایج جستجو برای: ایمونوگلوبولینe ige
تعداد نتایج: 15373 فیلتر نتایج به سال:
Microbial exposure following birth profoundly impacts mammalian immune system development. Microbiota alterations are associated with increased incidence of allergic and autoimmune disorders with elevated serum IgE as a hallmark. The previously reported abnormally high serum IgE levels in germ-free mice suggests that immunoregulatory signals from microbiota are required to control basal IgE lev...
Immunoglobulin E (IgE) can be highly elevated in the airway mucosa independently of IgE serum levels and atopic status. Mostly, systemic markers are assessed to investigate inflammation in airway disease for research or clinical practice. A more accurate but more cumbersome approach to determine inflammation at the target organ would be to evaluate markers locally. We review evidence for local ...
Mast cells are the major effector cells for immediate hypersensitivity and chronic allergic reactions. These cells accumulate in mucosal tissues of allergic reactions, where immunoglobulin E (IgE) is produced locally. Here we provide evidence that, in addition to antigen that can attract IgE-bound mast cells, the type of IgE molecules that efficiently activate mast cells can promote the migrati...
The mechanisms involved in the maintenance of memory IgE responses are poorly understood, and the role played by germinal center (GC) IgE(+) cells in memory responses is particularly unclear. IgE(+) B cell differentiation is characterized by a transient GC phase, a bias toward the plasma cell (PC) fate, and dependence on sequential switching for the production of high-affinity IgE. We show here...
Patients with atopic dermatitis (AD) tend to have greatly elevated levels of serum immunoglobulin E (IgE). However, the role of IgE in the pathogenesis of AD is debated. This investigator-initiated open-label pilot study evaluates an anti-IgE-treatment approach by combining extracorporeal immunoadsorption and anti-IgE antibody omalizumab in 10 patients with severe, therapy-refractory AD. IgE le...
air pollutants are reported to increase the specific ige response to allergens. clinical tests and immonoblotting were performed with pollen grains of spartium junceum. to identify allergens and to determine the effect of air pollutants on the allergenicity of the pollen extracts, the pollen extracts were injected intraperitoneally and intracutaneously to guinea pigs. injection of the pollen ex...
background: hyper ige syndrome (hies) is a rare primary immune deficiency, described as job`s syndrome characterized by increased serum levels of ige, eczema, recurrent cutaneous and pulmonary infections. in this paper, we presented a case of hyper ige syndrome.case presentation: a 16-year-old iranian boy presented with a one year history of skin lesions in knees and elbows was diagnosed of pso...
سابقه و هدف: در تحقیقات مختلفی که تاکنون در زمینه ایمونوپاتوژنز وضعیت های مختلف پالپ دندان صورت گرفته، به پالپ پولیپ یا پالپیت هیپرپلاستیک توجه چندانی نشده است. لذا هدف از انجام این تحقیق بر پایه تعیین رابطه میان حضور و غلظت IgE و هیستامین پالپ با پالپ پولیپ بنا نهاده شد.مواد و روشها: روش این مطالعه بصورت تحلیلی و مورد شاهدی بود. برای این منظور، 17 نمونه پالپی مبتلا به پالپ پولیپ و 16 نمونه پال...
Background & Aim: and achieving safe prophylactic and therapeutic procedures is the main aim of the investigators. CpGoligodeoxynucleotides (CpG ODN) which modulate the immune responses and change the cytokine patterns by severalmechanisms are among these procedures.Worldwide increasing number of allergic disorders is one of the most important health challenges,Material and Method: Chenopodium ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید