introduction and aims: the northeastern region of iran has some of the highest rates of esophageal squamous cell carcinoma (escc) in the world. materials and methods: to investigate the role of polycyclic aromatic hydrocarbons (pahs) in the etiology of escc in northeastern iran, we measured urine 1-hydroxypyrene glucuronide (1-ohpg), a stable pah metabolite, in 99 inhabitants of this area. resu...

introduction: recently, due to the special characteristics of 166ho and chitosan, 166ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. this complex has been lately prepared with high radiochemical purity in our lab. the preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and normal tissues before...

in this study, aluminosilicate mcm-41 has been found to be an efficient catalyst for reaction betweendifferent benzaldehyde derivatives and 5,5-dimethyl-1,3-cyclohexanedione to give open chain analogue of1,8-dioxo-octahydroxanthene in excellent yields. no evidence for the formation of cyclization products wasobserved. the catalyst can be used several times after recovery.

a green and convenient protocol is described for the preparation of 1-(alkylamino)-3-(1,3-dioxoisoindolin-2-yl)-2-methyl-1-oxopropan-2-yl benzoates via one-pot three-component reaction between 2-(2-oxopropyl)isoindoline-1,3-dione, an alkyl isocyanide and an aromatic carboxylic acid in water at room temperature. the methods used to follow the reactions are tlc and nmr, which indicated that there...

the aqueous electrochemistry of a number of anthraquinone derivatives was studied by using cyclic voltammetry at the surface of carbon paste electrode (cpe). from measurements of the half-wave potential as a function of ph, the potential - ph diagrams were constructed for each compound. the values of formal potentials and the pk'a of some different redox and acid-base couples involved in each c...

an efficient synthesis of some novel coumarin derivatives via 1, 4- michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (csa) under solvent free conditions is described. the corresponding michael addition products were obtained in good to excellent yield. the synthesized compounds were screened for their antibacterial activity against e. coli, s. aureus and an...

background and aim: 2,4-dichlorophenol (dcp) is a compound  generated in a variety of industrial processes and also by chlorine disinfection of water polluted with phenolic compounds . dumping of dcp into the environment and water resources is of great concern because of the compound's intense odor and toxicity. dcp is very soluble and resistant to biodegradability so it cannot be removed ...