background: the autoimmune disease known as idiopathic (immune thrombocytopenic purpura thrombocytopenic purpura (itp) is clinically defined by a low numbers of platelets in the circulation blood. this study aimed to isolate autoantibodies made against the platelet glycoproteins using platelets from healthy volunteers, to determine their specificity and further elucidate their effects on platel...

mediastinal neoplasms are uncommon tumors that can occur at any age but are most common through the fifth decades of life. a wide variety of systemic disorders are associated with 71% of thymomas. the symptoms of these as sociated disorders often lead to the original discovery of the mediastinal tumor. a 35-year-old female with petechia and purpura was admitted to sina hospital of the city of h...

itp is an autoimmune blood disorder in which platelet destruction is mediated by anti-platelet antibodies. the mechanisms of anti-platelet antibodies development are still a little known. the rate of some bacterial or viral agents in cause of itp is well known. recently, some study proposed that h pylori infection may be associated with itp and h pylori eradication can improves platelet counts ...

background: pentoxifylline (px) is a methyl xanthine derivative that influences the sperm motion characteristics and l-carnitine (l-c) is an amino acid that is naturally produced in the body. in general, separate administration of px and l-c has been reported to be effective on preserving sperm motility in vitro, and also when is consumed orally by the idiopathic oligoasthenoteratozoospermia (i...

juvenile idiopathic arthritis is the leading cause of hip replacement in young children. however, arthroplasty in this population is challenging with several concerns about quality of the growing bone, young age for revision surgery, and difficulties in potential several revisions. in this study we introduce a case of a 12-year old who is one of the youngest patients to undergo revision hip art...

conclusions ipah is associated with subclinical hypothyroidism and low patient functional capacity, and is more common in rv failure. results in this research, 84.8% of the participants were women. the mean pap was 51.6 mmhg (31-87) and mean thyroid stimulating hormone (tsh) level was 4.2 miu/ml (0.7 - 10). subclinical hypothyroidism was detected in 26 patients (49.1%). there were significant c...

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background: the most common neurologic manifestation of gluten sensitivity is ataxia, which accounts for up to 40% of idiopathic sporadic ataxia. timing of diagnosis of gluten ataxia is vital as it is one of the very few treatable causes of sporadic ataxia and causes irreversible loss of purkinje cells. antigliadin antibody (aga) of the igg type is the best marker for neurological manifestation...