In this editorial to the IJHCS Special Issue on Animal-­‐Computer Interaction (ACI), we provide an overview of the state-­‐of-­‐the-­‐art in this emerging field, outlining the main scientific interests of its developing community, in a broader cultural context of evolving human-­‐animal ...

Autologous chondrocyte implantation (ACI) is used widely as a treatment for symptomatic chondral and osteochondral defects of the knee. Variations of the original periosteum-cover technique include the use of porcine-derived type I/type III collagen as a cover (ACI-C) and matrix-induced autologous chondrocyte implantation (MACI) using a collagen bilayer seeded with chondrocytes. We have perform...

Background: Cyclosporine-A (CsA) is an immunosuppressive drug used in organ transplantation. Side effects of CsA such as body weight loss and decreased fertility rate have been reported. Satureja hortensis is a therapeutic plant with antioxidant properties. Materials and Methods: 24 adult male rats weighing 200±20 gr were divided into three groups (n=8): control group which received no treatmen...

BACKGROUND Autologous chondrocyte implantation (ACI) can be used in the treatment of focal cartilage injuries to prevent the onset of osteoarthritis (OA). However, we are yet to understand fully why some individuals do not respond well to this intervention. Identification of a reliable and accurate biomarker panel that can predict which patients are likely to respond well to ACI is needed in or...

 Background: Cyclosporine A (CsA) is a potent immunosuppressant drug with therapeutic and toxic actions. The use of CsA is limited by its toxicity. Several researchers had proposed that oxidative stress could play an important role in CsA-induced toxicity. Arbutin has recently been shown to possess antioxidative and free radical scavenging abilities.The present study was designed to investigate...

AIMS The interaction between lectin-like oxidized low density lipoprotein (LDL) receptor-1 (LOX-1) and oxidized LDL (ox-LDL) has been viewed as an important pathogenic factor for cardiovascular diseases. This study aimed to explore the association of a functional polymorphism rs1050283 in the 3'-untranslated region of the LOX-1 gene with atherosclerotic cerebral infarction (ACI) susceptibility,...

Autologous chondrocyte implantation (ACI) and mosaicplasty are both claimed to be successful for the repair of defects of the articular cartilage of the knee but there has been no comparative study of the two methods. A total of 100 patients with a mean age of 31.3 years (16 to 49) and with a symptomatic lesion of the articular cartilage in the knee which was suitable for cartilage repair was r...

The adjacent channel interference (ACI) can result in a reduced network capacity in a multioperator WCDMA/FDD environment. This paper is devoted to the study of the ACI, using a static simulator. Simulations were performed in order to identify particular scenarios and network compositions where ACI plays a major role in the system capacity. On the basis of the results, the authors identify the ...

We previously showed that lysophosphatidic acid (LPA) and an adenylyl cyclase inhibitor (ACI) stimulate mitogenic activation of senescent human diploid fibroblasts. Because the modulation of cell proliferation may affect wound healing in aged organisms, we studied the effects of LPA and ACI on in vivo skin wound healing in aged Fisher 344 rats. We found that, in aged rats, wound healing improve...