buccoadhesive drug delivery systems have distinct advantages in comparison with oral administration. plant exudates like gum or mucilage are being studied for their use as pharmaceutical adjuvant. the aim of this study is to evaluate the properties of the plantago major seed mucilage as a mucoadhesive agent and propranolol hydrochloride is chosen as a model drug. mucoadhesive tablets of propran...

in this work we sought to determine whether vesicles (liposomes/niosomes) were able to enhance finasteride concentration in the dermis layer, including the pilosebaceous units (psu). such enhancement could be beneficial in the treatment of some androgen-related skin disorders. hamster flank skin was used to study  3hfinasteride permeation via vesicles and a hydroalcoholic solution (ha). the dru...

We present an analysis of the dipole straylight contamination (DSC) for spinning space-missions designed to measure CMB anisotropies. Although this work is mainly devoted to the Planck project, it is relatively general and allows to focus on the most relevant DSC implications. We first study a simple analytical model for the DSC in which the pointing direction of the main spillover can be assum...

Differential Scanning Calorimetry (DSC) of intact Escherichia coli (E. coli) was used to identify non-lipidic targets of the antimicrobial peptide (AMP) MSI-78. The DSC thermograms revealed that, in addition to its known lytic properties, MSI-78 also has a striking effect on ribosomes. MSI-78's effect on DSC scans of bacteria was similar to that of kanamycin, an antibiotic drug known to target ...

Arrays of thin-film solar cells based on dye-sensitised nanocrystalline oxides (DSC) promise low-cost electricity especially where continuous direct insolation is unavailable. However, the optimisation of arrays of DSC is not straightforward because of the lower power levels obtained and the corresponding increased stringency needed when calculating the production tolerances permissible in the ...

BACKGROUND AND PURPOSE QUASAR is a particular application of the ASL method and facilitates the user-independent quantification of brain perfusion. The purpose of this study was to assess the intermodality agreement of TBF measurements obtained with ASL and DSC MR imaging and the inter- and intraobserver reproducibility of glioma TBF measurements acquired by ASL at 3T. MATERIALS AND METHODS T...

Discontinuously reinforced aluminum metal matrix composites (MMCs) with about 20 vol.% reinforcement produced by powder metallurgy (PM) are attractive for many structural applications because of their high specific strength and stiffness. While they exhibit reduced ductility and toughness at room temperature, many of them can be superplastically deformed at high-strain rates in the vicinity of ...

High body mass index (BMI) has been inconsistently associated with overall survival (OS) of digestive system cancers (DSCs). This meta-analysis was conducted to investigate whether high BMI was associated with DSCs prognosis. 34 studies were accepted, with a total of 23,946 DSC cases. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) for OS in BMI categories from individual studies we...