Blood-brain barrier (BBB) disruption is a common feature of numerous neurologic disorders. A fundamental question in these diseases is the extent inflammatory immune cells contribute to CNS vascular permeability. We have previously shown that CD8 T cells play a critical role in initiating BBB disruption in the peptide-induced fatal syndrome model developed by our laboratory. However, myelomonoc...

We investigate the rare baryonic exclusive decays of Λb → Λll (l = e, μ, τ) with polarized Λ. Under the approximation of the heavy quark effective theory (HQET), in the standard model we derive the differential decay rates and various polarization asymmetries by including lepton mass effects. We find that with the long-distance effects the decay branching ratios are 5.3× 10 for Λb → Λll (l = e,...

We study the classical Antonov problem (of retrieving the statistical equilibrium properties of a self-gravitating gas of classical particles obeying Boltzmann statistics in space and confined in a spherical box) for a rotating system. It is shown that a critical angular momentum λ c (or, in the canonical language, a critical angular velocity ω c) exists, such that for λ < λ c the system's beha...

In this article, we study the existence of positive solutions for the coupled elliptic system −∆u = λ(f(u, v) + h1(x)) in Ω, −∆v = λ(g(u, v) + h2(x)) in Ω, u = v = 0 on ∂Ω, under certain conditions on f, g and allowing h1, h2 to be singular. We also consider the system −∆u = λ(a(x)u+ b(x)v + f1(v) + f2(u)) in Ω, −∆v = λ(b(x)u+ c(x)v + g1(u) + g2(v)) in Ω, u = v = 0 on ∂Ω, and prove a Rabinowitz...

The effective use of complex fenestration systems in buildings requires knowledge of their optical spectral and directional properties. While the directional properties are commonly assessed by the measurement of bidirectional transmission or reflection distribution functions, the addition of spectral information would significantly aid in the design and analysis of such systems. This paper des...

Two important decisions in supply chains and logistics systems design are the supplier selection order allocation (SS&OA) problem vehicle routing (VRP). Supply disruption may reduce capacity of suppliers, transportation network decrease number vehicles fleet disrupt some routes. Also, increasing environmental regulations awareness makes companies pay more attention to green chain management (GS...