Introduction: A high risk for development of severe side effects after radiotherapy may be correlated with high cellular radiosensitivity. To enhance radiation therapy efficiency a fast and reliable in-vitro test is desirable to identify radiosensitive patients. The aim of present study was to identify the mechanism of radiation induced DNA double-strand breaks (DSBs) and DSB r...

Several classes of exact solutions to the Einstein field equations coupled with either a massless scalar field or a radiation fluid are given, and their main properties are studied. It is found that some represent the formation of black holes due to the gravitational collapse of the matter fields. When the spacetimes have continuous self-similarity (CSS), the masses of black holes take a scalin...

INTRODUCTION Proton radiation offers physical advantages over conventional radiation. Radiosensitivity of human 59M ovarian cancer and HTB140 melanoma cells was investigated after exposure to γ-rays and protons. MATERIAL AND METHODS Irradiations were performed in the middle of a 62 MeV therapeutic proton spread out Bragg peak with doses ranging from 2 to 16 Gy. The mean energy of protons was ...

Ionizing radiation from both natural and man-made sources can affect the various organs and tissues of the body. Radiation processing is an expanding technology with numerous applications in many domains, including health care products sterilization, sewage and hospital waste treatment, polymer modifications, and food processing [1]. Moreover, real-time radiation detectors have become essential...

We present numerical simulation of bulk Lorentz factor of relativistic electron-positron jet driven by Compton rocket effect from accretion disc radiation. The plasma is assumed to have a power-law distribution n e (γ) ∝ γ −s whith 1 < γ < γ max and is continuously reheated to compensate for radiation losses. We include full Klein-Nishina (hereafter KN) cross section, and study the role of ener...

Our knowledge of the high-energy universe is undergoing a period of rapid change as new astronomical detectors of high-energy radiation start to operate at their design sensitivities. Now is a boomtime for highenergy astrophysics, with new discoveries from Swift and HESS, results from MAGIC and VERITAS starting to be reported, the upcoming launches of the γ-ray space telescopes GLAST and AGILE,...

We consider the neutron star (NS) of the magnetar type inside the massive binary system. We determine the conditions under which the matter from the stellar wind can penetrate the inner magnetosphere of the magnetar. At some distance from the NS surface, the magnetic pressure can balance the gravitational pressure of the accreting matter creating very turbulent, magnetized transition region. It...

Relativistic electron-positron winds with strong magnetic fields are considered as a source of radiation for cosmological γ-ray bursters. Such a wind is generated by a millisecond pulsar with a very strong magnetic field. An electronpositron plasma near the pulsar is optically thick and in quasi-thermodynamic equilibrium. It is shown that the main part of radiation from the pulsar wind is nonth...

BACKGROUND High expression of constitutive histone γ-H2AX, a sensitive marker of DNA damage, might be indicative of defective DNA repair pathway or genomic instability. 53BP1 (p53-binding protein 1) is a conserved checkpoint protein with properties of a DNA double-strand breaks sensor. This study explores the relationship between the clinical radiosensitivity of tumor patients and the expressio...