background: the canonical wnt signal transduction (or the wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. beta-catenin is the central component of this signaling pathway. the activation of wnt/β-catenin signaling results in the cytoplasmic and nuclear accumulation of β-catenin. in the nucleus, β-catenin interacts with the tcf/lef transcription fa...

The chemical composition of plant polyphenols Plantago major L. and lanceolata growing in Uzbekistan was studied. More than 20 compounds, including 7 flavonoids, 9 phenolic acids, 8 hydrolysable tannins, the ages which have been determined using physicochemical methods research isolated from plants. From P. L., along with well-known such as gallic acid, rutin, luteolin, isorhamnetin, hyperoside...

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background extended-spectrum β-lactamase (esbl) production is the major resistance mechanism to β-lactam antibiotics in enterobacteriaceae. in addition, emergence of plasmid-mediated quinolone resistance (pmqr) in esbl-producing isolates has become a global threat for treatment of these infections. objectives we investigated the association between esbl production and quinolone resistance in ur...

Background: Sexual health is an important component of general health.
 Objective: To evaluate sexual function and quality life (SQOL) in women during the COVID-19 pandemic.
 Methods: This descriptive, cross-sectional study was conducted Turkey. Data were collected via a Visual Analog Scale (VAS), Female Function Index (FSFI), Quality Life–Female (SQOL-F) questionnaire.
 Results:...

Purpose: The purpose of this study was to examine the correlations among perceived health status, stress, daily life changes, physical distancing, depression, and determine associated fctors depression fo older adults in COVID-19.Methods: This conducted on 42,448 persons aged 65 years above who participated 2020 Community Health Survey Data analysis done with SAS 9.4.Results: factors related co...