Respiratory syncytial virus (RSV) is estimated to claim more lives among infants <1 year old than any other single pathogen, except malaria, and poses a substantial global health burden. Viral entry is mediated by a type I fusion glycoprotein (F) that transitions from a metastable prefusion (pre-F) to a stable postfusion (post-F) trimer. A highly neutralization-sensitive epitope, antigenic site...

This dissertation provides an overview on the problem of electronic component obsolescence from a military product support perspective. By assessing applicable literature as well as feedback and lessons learned from relevant support projects, a strategy for the management of component obsolescence is proposed. The aim of the research is to provide a definition of component obsolescence drivers ...

Auroral roar, a narrowband (Sf/f < 0.1) emission near 2 and 3 times the ionospheric electron gyrofrequency (2f• and 3f•), is observed with a meridional chain of LF/MF/HF radio receivers located in northern Canada spanning 67 ø to 79 ø invariant latitude. Observations of these emissions are compared with the auroral electrojet location inferred from the Canadian Auroral Network for the OPEN Prog...

We heated mixtures of sulfur and Na-bearing silicates in evacuated silica glass capsules to temperatures b tween 600øC and 950 ø C. At or above 850 ø C, Na-silicate glass reacts with elememal S to form a (Na, K) sulfide. Mobilization of this phase may account for the presence of Na and K on the surface of Io, and hence in the material sputtered into the Jovian magnetosphere.

We excite ZnO samples with two-cycle optical pulses directly from a mode-locked oscillator with average powers of several tens of milliwatts. The emitted light reveals peaks at the carrier-envelope offset frequency f(ø) and at 2f(ø) in the radio-frequency spectra. These peaks can still be detected in layers as thin as 350 nm-a step toward determining the carrier-envelope offset phase itself.

By focusing on time sequences of basin-average and global-average upper ocean temperature (i.e., from 40øS to 60øN) we find temperatures responding to changing solar irradiance in three separate frequency bands with periods of >100 years, 18-25 years, and 9-13 years. Moreover, we find them in two different data sets, that is, surface marine weather observations from 1990 to 1991 and bathythermo...