Syntrophins are scaffold proteins that regulate the subcellular localization of diacylglycerol kinase zeta (DGK-zeta), an enzyme that phosphorylates the lipid second-messenger diacylglycerol to yield phosphatidic acid. DGK-zeta and syntrophins are abundantly expressed in neurons of the developing and adult brain, but their function is unclear. Here, we show that they are present in cell bodies,...

abstractin the last step of desolvation method for preparation of albumin nanoparticles, glutaraldehyde (ga) is added to stabilize the newly formed nanoparticles. due to undesirable effects of ga, the objective of this study was to evaluate alternative methods of crosslinking including ultraviolet (uv) irradiation, adding of glucose and combination of both methods. the nanoparticles were prepar...

We use the generalized zeta function regularization method to compute the one-loop quantum correction to the masses of the TK1 and TK2 kinks in a deformation of the O(N) linear sigma model on the real line.

In this paper, we obtain the main term of the average stochastic complexity for certain complete bipartite graph-type spin models in Bayesian estimation. We study the Kullback function of the spin model by using a new method of eigenvalue analysis first and use a recursive blowing up process for obtaining the maximum pole of the zeta function which is defined by using the Kullback function. The...

In this paper we first establish the relation between the zeta-determinant of a Dirac Laplacian with the Dirichlet boundary condition and the APS boundary condition on a cylinder. Using this result and the gluing formula of the zetadeterminant given by Burghelea, Friedlander and Kappeler with some assumptions, we prove the adiabatic decomposition theorem of the zeta-determinant of a Dirac Lapla...

A precise zeta-function calculation shows that the contribution of the vacuum energy to the observed value of the cosmological constant can possibly have the desired order of magnitude albeit the sign strongly depends on the topology of the universe. The non-renormalizable, infinite contributions which have been recently shown to occur when one physically imposes boundary conditions on quantum ...

The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, play a major role in migration, retention, and development of hematopoietic progenitors in the bone marrow. We report the direct involvement of atypical PKC-zeta in SDF-1 signaling in immature human CD34(+)-enriched cells and in leukemic pre-B acute lymphocytic leukemia (ALL) G2 cells. Chemotaxis, cell polarization, an...

This paper draws connections between the double shuffle equations and structure of associators; Hain and Matsumoto’s universal mixed elliptic motives; and the Rankin–Selberg method for modular forms for SL2(Z). We write down explicit formulae for zeta elements σ2n−1 (generators of the Tannaka Lie algebra of the category of mixed Tate motives over Z) in depths up to four, give applications to th...

gene therapy is in its development stage as a novel method for cancer treatment. liposomes look promising as gene delivery vectors; however, investigations have shown that these vesicles are not doing well in some cases. it was decided here to investigate the possibility of augmentation of liposomal gene delivery by chemical penetration enhancers.cationic liposome containing antisense oligonucl...

this article presents the method of extraction-preconcentration of lead, cadmium, and nickel ions from food samples using the ghezeljeh montmorillonite nanoclay (geleh-sar-shoor) as a new native adsorbent in batch single component systems. the extraction-preconcentration of heavy metals were carried out by applying the solid phase extraction (spe) method followed by atomic absorption spectrosco...