Centromeres were familiar to cell biologists in the late 19th century, but for most eukaryotes the basis for centromere specification has remained enigmatic. Much attention has been focused on the cenH3 (CENP-A) histone variant, which forms the foundation of the centromere. To investigate the DNA sequence requirements for centromere specification, we applied a variety of epigenomic approaches, ...

BACKGROUND Yeast-like fungi inhabit soils throughout all climatic zones in a great abundance. While recent estimations predicted a plethora of prokaryotic taxa in one gram of soil, similar data are lacking for fungi, especially yeasts. METHODOLOGY/PRINCIPAL FINDINGS We assessed the diversity of soil yeasts in different forests of central Germany using cultivation-based techniques with subsequ...

Cancer disease is a variety of diseases that are uncontrolled development, and non-natural cell disturbance.This can lead to death if the disturbance not controlled. The results indicate dangerous role fungiand bacteria associated with cancer patients.They were both Staphylococcus aureus, Str. mitis, mutansand Escherichia coli most common isolates patients. Candida albicans, C.krusei, C. glabra...

The FLO genes of Saccharomyces cerevisiae encode a family of proteins important in determining diverse aspects of cell-surface function. In this issue of Cell, Halme et al. show that both genetic and epigenetic mechanisms control expression of the FLO genes, thereby generating significant cell-surface diversity within a population of yeast cells.

Habitat distribution and seasonal occurrence of carabid beetles were determined using pitfall traps in 1999 and 2000 in the temperate forest zone of the Dongling Mountain, North China. Eight sites differing in vegetation and moisture were selected so as to represent four habitat types. Carabid assemblages of the six forested habitats (lowland, upland and coppice) were more similar to each other...

This paper presents a geomorphological map of the Hérens valley in the Western Swiss Alps. With an area of 270 km and altitudes ranging from 470 to 4357 m a.s.l., this valley is one of the main secondary catchments of the Upper Rhône valley. The high differences in altitudes, combined with a varied geology, create an important geomorphic diversity. The main processes active in mountain areas, t...

As troves of microbiome sequencing data provide improved resolution of patterns of microbial diversity, new approaches are needed to understand what controls these patterns. Many microbial ecologists are using cultivated model microbial communities to address this challenge. These systems provide opportunities to identify drivers of microbiome assembly, but key challenges and limitations need t...

Inositol pyrophosphates are unique signaling molecules implicated in the regulation of diverse cellular processes. Two new studies by Mulugu et al. (2007) and Lee et al. (2007) extend the biological and metabolic diversity of this class of molecules. They identify yeast Vip1 as a new inositol pyrophosphate synthase and show that the products of Vip1 activity regulate a cyclin/cyclin-dependent k...

In this study, we examined Sicilian-style green olive fermentations upon the addition of Saccharomyces cerevisiae UCDFST 09-448 and/or Pichia kudriazevii UCDFST09-427 or the lactic acid bacteria (LAB) Lactobacillus plantarum AJ11R and Leuconostoc pseudomesenteroides BGM3R. Olives containing S. cerevisiae UCDFST 09-448, a strain able to hydrolyze pectin, but not P. kudriazevii UCDFST 09-427, a n...