BACKGROUND Burkholderia pseudomallei are the causative agent of melioidosis. Increasing resistance of the disease to antibiotics is a severe problem in treatment regime and has led to intensification of the search for new drugs. Antimicrobial peptides are the most ubiquitous in nature as part of the innate immune system and host defense mechanism. METHODS Here, we investigated a group of veno...

BACKGROUND & OBJECTIVES Subinhibitory concentrations (sub-MICs) of antibiotics, although not able to kill bacteria, but influence bacterial virulence significantly. Fluoroquinolones (FQs) which are used against other bacterial pathogens creates resistance in non-targeted Streptococcus pyogenes. This study was undertaken to characterize the effect of sub-MICs of FQs on S. pyogenes biofilm format...

Purpose: In this study, it is aimed to prepare chitosan nanoparticles containing shRNA-VEGF and evaluate their bioactivity by in vitro cell culture studies perform mechanical characterization of nanoparticles.
 Material Methods: Ionic chelation method was used nanoparticles. The XTT assay assess the cytotoxic activity loaded NP on HeLa NIH 3T3 cells.
 Results: According results IC50 v...

The aim of the study is to evaluate ethanol extract Rheum ribes root (RTE), as well and young shoots (RYSE), for its chemical composition, antioxidant properties cytotoxic effects. Total polyphenols (TPC), total flavonoid (TFC), radical scavenging activity (DPPH), ferric reducing power (FRAP) extracts were determined using colorimetric methods. Mineral contents vitamin values samples by ICP-MS ...

1.Bartelt, D.C., S. Fidel, L.H. Farber, D.J. Wolff and R.L. Hammell. 1988. Calmodulin-dependent multifunctional protein kinase in A. nidulans. Proc. Natl. Acad. Sci. USA 85:3279-3283. 2.Bergen, L.G., A. Upshall and N.R. Morris. 1984. S-phase, G2, and nuclear division mutants of Aspergillus nidulans. J. Bacteriol. 159:114-119. 3.Dayton, J.S., M. Sumi, N.N. Namthakumar and A.R. Means. 1997. Expre...

The paper deals with the problem of modeling business rules (BR) in the business process management (BPM). The paper presents the challenges of BR modeling, and shows some disadvantages of existing, commonly used methods, such as the BPMN. As a solution, an approach based on the XTT/ARD expert system design and implementation method is outlined and discussed. The methods improve the design and ...

Burada, steroidal olmayan anti-enflamatuar ilaç niflumik asit ve 3-pikolin içeren yeni bir gümüş(I) kompleksi sentezlendi FT-IR, 1H NMR, elemental termik analiz teknikleri ile karakterize edildi. Bu teknikler, sentezlenen kompleksin formülünün [Ag(nif)(3-pic)] olduğunu gösterdi. Kompleks, ligand (niflumik asit) gümüş iyonlarının tek başına sitotoksik yeteneği, insan meme adenokarsinomu (MDA-MB-...

Persea gratissima known as avocado is a valuable plant. P. (PgO) oil used in traditional medicine to treat several health problems because of its numerous biological properties. source phytosterols and has effects antimicrobial, anti-inflammatory, anti-oxidant neuroprotective activities for vitro vivo models. The aim this study synthesize characterize the PgO loaded chitosan nanoparticles inves...