A significant increase in the severity of clinical manifestations various dermatoses accompanied by dry skin often increases feeling discomfort and itching skin, significantly reducing patient's quality life. This leads to search for effective ways correct dryness maintain proper functioning epidermal barrier dermatoses. The aim study was effect using a combined emollient, which includes compon...

INTRODUCTION Sj€ ogren syndrome is a systemic autoimmune disease characterized by dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia). Common cutaneous manifestations of Sj€ ogren syndrome include xerosis, annular erythema, hypergammaglobulinemic purpura, and immunologic inflammatory conditions such as vasculitis (leukocytoclastic and urticarial). The clinical manifestations of vas...

Melanonychia commonly appears as a longitudinal band, starting from the matrix and extending to the tip of the nail plate. Less often it presents a transverse band or may inolve whole nail plate. Cutaneous side effects of hydroxyurea are described in 13% of patients including increased pigmentation, hyperkeratosis, skin atrophy, xerosis, lichenoid eruptions, palmar and plantar keratoderma, cuta...

Xerosis is a common skin condition, occurring most often in the winter and in low relative humidity, which results in loss of moisture, cracking, and desquamation. Many emollient creams and lotions are available for use as preventive moisturizers. However, few controlled experiments have been published comparing the efficacy of active moisturizing products versus the vehicle used to deliver the...

In the past I5 years various types of scleral contact lenses have been developed for the treatment of pathological conditions of the cornea and conjunctiva. Our previous investigations found the hydrophilic corneo-scleral lens very effective in the treatment of various inflammatory and degenerative corneal changes (Krejci, I970, 1971). In our present study the Czech hydrophilic corneo-scleral c...