When considering the development of the grid as the universal computing infrastructure, one of the important issues that has to be faced is porting legacy codes to the grid. In this paper an approach to wrapping cluster codes as grid services using the latest generation of grid middleware is analyzed. This approach was derived from several experiments of wrapping legacy codes. The application-d...

Here we present a hybrid approach to functionalize multi-walled carbon nanotubes in aqueous solution, exploring a non-covalent binding strategy. We focus on formation of hybrid complexes consisting of carbon nanotubes decorated by single stranded DNA, non-covalently attached using surfactants as intermediate layers. Unlike single walled carbon nanotubes, revealing easy side wall wrapping of DNA...

Polymers stabilize the nanoparticles onto which they wrap, avoiding coagulation and undesired phase separation processes. Wrapping gives rise to hybrid colloids, is useful in bio-intended applications. In non-covalent interaction modes, polymers physically adsorb nanoparticles’ surface, NPs, some of their portions protrude outside. Both non-interacting parts free are contact with solvent, and/o...

How soft tubular aggregates interact with biomembranes is crucial for understanding the formation of membrane tubes connecting two eukaryotic cells, which are initially created from one cell and then connect with the other. On the other hand, recent experiments have shown that tubular polymersomes display different cellular internalization kinetics in their biomedical applications compared with...

BACKGROUND The management of mild to moderate dilatation of the ascending aorta of less than 5 cm is controversial, particularly when concomitant surgical correction of aortic valve is required. We investigate the impact of a simple method of aorta reduction using Dacron graft wrapping during aortic valve replacement on the rest of the aorta. METHODS We studied 14 patients who had ascending a...

Efficient neuronal conductance requires that axons are insulated by glial cells. For this, glial membranes need to wrap around axons. Invertebrates show a relatively simple extension of glial membranes around the axons, resembling Remak fibers formed by Schwann cells in the mammalian peripheral nervous system. To unravel the molecular pathways underlying differentiation of glial cells that prov...

Molecularly targeted treatment of malignancy requires a careful control of drug specificity. We review recent advances in this area focusing on a particular marker for ligand-target associations: the poorly wrapped hydrogen bond or dehydron, a packing defect in the protein target. Dehydrons promote their own dehydration and are generally not conserved across homologs. Thus, the so-called "wrapp...

Single-walled carbon nanotubes (SWCNTs) demonstrate a unique combination of optical, chemical, and physical properties that render them suitable for a variety of sensing applications. Their photostable near-infrared (nIR) fluorescence emissions are highly sensitive to perturbations in the surrounding SWCNT environment, enabling optical sensors with single-molecule detection limits. Despite thes...

Analysis of convex polyhedra using abstract interpretation is a common and powerful program analysis technique to discover linear relationships among variables in a program. However, the classical way of performing polyhedral analysis does not model the fact that values typically are stored as fixed-size binary strings and usually have a wrap-around semantics in the case of overflows. In embedd...

Transcription ternary complexes of Escherichia coli RNA polymerase and yeast RNA polymerase III have been analyzed by atomic force microscopy. Using the method of nucleotide omission and different DNA templates, E.coli RNAP has been stalled at position +24, +70 and +379 and RNAP III at position +377 from the starting site. Conformational analysis of E.coli RNAP elongation complexes reveals an a...