RESULTS: The majority of flaps were for lower extremity trauma wounds (74), followed by upper extremity trauma wounds (8), scalp tumor defects (4), and one torso wound. There were 7 flap losses, but of these, 4 were due to noncompliance with postoperative immobilization/elevation orders; excluding these 4 failures for which the NPD was clearly not a factor, the flap success rate was 96.4%. Skin...

Microbial infections delay wound healing, but the effect of the composition of the wound microbiome on healing parameters is unknown. To better understand bacterial communities in chronic wounds, we analyzed debridement samples from lower-extremity venous insufficiency ulcers using the following: conventional anaerobic and aerobic bacterial cultures; the Ibis T5000 universal biosensor (Abbott M...

wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. in this study we aimed to determine the effect of simvastatin on wound healing process in...

burns are a worldwide problem. the incidence of severe burns has been higher than the combined incidence of tuberculosis and hiv infections. throughout history there have been many different treatments prescribed for burns. the canon is the masterpiece of avicenna’s medical books. the canon includes a description of 785 simple drugs. avicenna believed in burn treatment, which follows two goals....

conclusions transdermal wound oxygen therapy can effectively promote wound healing in patients with pressure ulcers. results after 12 days of wound oxygen therapy, the number of patients with complete wound healing in the experimental group was significantly greater than that of the control group. moreover, the total mean of wound area in the experimental group was significantly lower than that...

Studies in our wound ballistics laboratory have shown that excellent healing can occur in complicated assault rifle wounds that are free of tension and well drained. A conservative approach to debridement and excision of tissue in uncomplicated extremity wounds may be a valid and resource-saving technique.

BACKGROUND Aortoiliac occlusive disease, which is also referred to as Leriche syndrome, is a chronic atherosclerotic occlusive disease that occurs at the level of the aortic bifurcation. It is often thought to present with a triad of clinical symptoms: (1) intermittent lower extremity vascular claudication, (2) impotence, and (3) weak/absent femoral pulses. CASE PRESENTATION We report a case ...

t rue saccular aneurysm is exceptional in coarctation of aorta in children. a 6-year-old girl with headache and systemic arterial hypertension referred to our center for cardiovascular evaluation. physical examination revealed high blood pressure and weak lower extremity pulses. two-dimensional and doppler echocardiography and angiography demonstrated a saccular aneurysm of the descending aorta...

Left forelimbs of adult newts were repeatedly denervated prior to and following amputation. Limb amputations were performed at 7-, 14-, 21-, 27-and 45-day intervals after the initial denervation. Regeneration was found in the sham-denervated and control animals but did not occur in any of the experimental cases; instead cicatrix formation and dermal wound healing ensued. Soft-tissue dedifferent...