BACKGROUND Although both cognitive therapy (CT) and interpersonal psychotherapy (IPT) have been shown to be effective treatments for major depressive disorder (MDD), it is not clear yet whether one therapy outperforms the other with regard to severity and course of the disorder. This study examined the clinical effectiveness of CT v. IPT in a large sample of depressed patients seeking treatment...

While the efficacy of cognitive-behavioral treatment (CBT) approaches for childhood functional abdominal pain (FAP) is well-established for child outcomes, only a few studies have reported on parent-specific outcomes. This randomized controlled pilot trial analyzed effects of a group CBT on maternal variables (i.e., pain-related behavior, worries and self-efficacy, as well as general psychosoci...

Abstract Land evaluation is a key factor in land-use spatial planning, affecting both success and sustainability. This study showcases the value of using multi-criteria (MCE) multi-objective land allocation (MOLA) GIS decision-making tools determine most favorable development various types, for Qaleh Ganj County Iran. Weighted linear combination (WLC) ordered weighted averaging (OWA) were used ...

Background: Community-dwelling older adults with early cognitive deficits experience less efficiency in performing everyday life tasks, resulting decreased satisfaction and other adverse psychological outcomes. Mindfulness training has been linked to improvements and, most recently, identified as a potential intervention supporting performance of activities. Objective: This study aimed evaluate...

Cell-fate decisions in metazoans are frequently guided by the Notch signalling pathway. Notch signalling is orchestrated by a type-1 transmembrane protein, which, upon interacting with extracellular ligands, is proteolytically cleaved to liberate a large intracellular domain [NICD (Notch intracellular domain)]. NICD enters the nucleus where it binds the transcription factor CSL (CBF1/suppressor...

Persons with posttraumatic stress disorder (PTSD) have been shown to display elevated baseline cardiovascular activity and a heightened physiological reactivity to trauma-related stimuli. Study 1 examined differences in baseline heart rate (HR) and HR reactivity in 68 survivors of motor vehicle accidents (MVAs) and healthy controls without MVA. MVA survivors with PTSD (n=26), subsyndromal PTSD ...

The GIS-multicriteria decision analysis (GIS-MCDA) technique is increasingly used for landslide hazard mapping and zonation. It enables the integration of different data layers with different levels of uncertainty. In this study, three different GIS-MCDA methods were applied to landslide susceptibility mapping for the Urmia lake basin in northwest Iran. Nine landslide causal factors were used, ...

We often learn and recall long sequences in smaller segments, such as a phone number 858 534 22 30 memorized as four segments. Behavioral experiments suggest that humans and some animals employ this strategy of breaking down cognitive or behavioral sequences into chunks in a wide variety of tasks, but the dynamical principles of how this is achieved remains unknown. Here, we study the temporal ...

Experimental data of the DNA cyclization (J-factor) at short length scales exceed the theoretical expectation based on the wormlike chain (WLC) model by several orders of magnitude. Here, we propose that asymmetric bending rigidity of the double helix in the groove direction can be responsible for extreme bendability of DNA at short length scales and it also facilitates DNA loop formation at th...

Program Mission: Students in WLC degree programs acquire functional language abilities, as well as a deeper understanding of the complexities of cultural difference. WLC's interdisciplinary focus aims at integrating the study of language and culture with the analysis of social, historical, political and artistic phenomena. The learning outcomes reflect the fact that as a result of majoring in t...