In this review article, the traditional viewpoint of how neurulation occurs is evaluated in light of recent advances. This has led to the formulation of the following fundamentals: (1) neurulation, specifically neural plate shaping and bending, is a multifactorial process resulting from forces both intrinsic and extrinsic to the neural plate; (2) neurulation is driven by both changes in neuroep...

BACKGROUND At the hilum of the liver, there is a structure called the hilar plate, which is of great surgical importance because all variations in the bile ducts and blood vessels occur within this region. The Rex-Cantlie line does not always pass the point of portal bifurcation. Classifying portal vein (PV) variations based on the shape and origin of anterior sectoral trunk (AST) within the he...

Transgenic mice were generated to permit the targeted ablation of cortical preplate cells at the time they are born. In these mice, the 1.3 kb golli promoter of the myelin basic protein gene was used to drive the herpes simplex virus thymidine kinase (TK) transgene in cortical preplate cells. Heterozygous transgenic pairs were bred, and pregnant dams were treated with ganciclovir at embryonic d...

Patterns of neuronal differentiation and axon outgrowth were examined in regenerated neural tissue of the hindbrain of the chicken embryo. Specific regions of the hindbrain neural tube corresponding to identified rhombomeres were selectively removed unilaterally by microsurgery. Of the embryos that survived, about 35% exhibited regulative regeneration, wherein the missing hemi-rhombomere was re...

An experiment is described in which monodisperse dust grains are levitated within a dc sheath above a conducting plate in argon plasma. For plate bias voltages that are not too negative ~>210 electron temperatures!, the observed dust levitation heights are near to values calculated from a model combining equations for the sheath with those for grain charging. When the plate is more negatively b...

Sycamore suspension callus cells have been partially synchronized to give a culture with a rmtotic index of 15 %. Living dividing cells of the culture have been examined with Nomarski differential interference optics and a comparable study made on fixed cells with the electron microscope. An organized band of reticulate cytoplasm partially encircles the nucleus at mitosis. The cell divides by t...

Despite significant progresses, cell-based assays still have major limitations part to because of their plate format. Here, we present a wall-less plate technology based on unique liquid dynamics named DropArray that takes advantage of hydrophobic and hydrophilic surface properties. Liquid velocities within the DropArray plate were quantified through fluid dynamics simulation and complete reten...

A slit in a thick metal plate that is extremely subwavelength will not transmit microwaves polarized parallel to it. It is shown here that cuts perpendicular to the slit allow parallel polarized radiation to resonantly transmit. Furthermore, a zero-order mode may be excited within the slit, the frequency of which, to first order, is independent of the plate depth. Remarkably, for this novel typ...

Title of Ph.D. Dissertation: THIN TWO-PHASE HEAT SPREADERS WITH BOILING ENHANCEMENT MICROSTRUCTURES FOR THERMAL MANAGEMENT OF ELECTRONIC SYSTEMS Sunil S Murthy, Doctor of Philosophy, 2004 Dissertation directed by: Professor Yogendra K. Joshi Department of Mechanical Engineering The current study goes over a design methodology for thin, two-phase heat spreaders for space constrained cooling appl...

Understanding the genetic basis of traits involved in adaptive divergence and speciation is one of the most fundamental objectives in evolutionary biology. Toward that end, we look for signatures of extreme plate loss in the genome of freshwater threespine sticklebacks (Gasterosteus aculeatus). Plateless stickleback have been found in only a few lakes and streams across the world; they represen...