The extravascular penetration of ceftizoxime and cefotaxime was studied in a rabbit subcutaneous Visking chamber model. Four rabbits, implanted with four chambers each, received each drug intramuscularly at a dose of 50 mg/kg every 3 hours for eight doses. Serum drug concentrations were measured after the eighth dose, and extravascular (chamber) concentrations were measured after the first and ...

OBJECTIVE To characterize out-of-hospital cardiac arrest (OHCA) and factors that affect survival in a medium sized city that uses system status management for dispatch. METHODS A retrospective cohort study of all adult OHCA patients treated by EMS between 1998 and 2001 was conducted using Utstein definitions. The primary endpoint was 1-year survival. RESULTS Of the 1177 patients who experie...

BACKGROUND Adenoid hypertrophy may cause sleep-disordered breathing and altered craniofacial growth. The authors conducted a study to gauge the accuracy of alternative tests compared with nasoendoscopy (reference standard) for screening adenoid hypertrophy. METHODS The authors conducted a systematic review that included searches of electronic databases, hand searches of bibliographies of rele...

Esta investigación analiza la consideración de diversidad familiar en América del Sur. Se ha realizado una revisión sistemática literatura (n=41) y se han analizado, por cada país, constituciones (n=10); censos (n=20); el cuerpo normativo (n=93); políticas sociales (n=67). Los resultados presentan forma comparada países. El principal hallazgo es escaso reconocimiento a familiar.

BACKGROUND For a quicker delivery of laboratory test results to the hospital emergency department (ED), we implemented an autoverification system based on the reference change value (RCV). The aim of this study was to assess how the RCV based autoverification reflected on turnaround time (TAT) and on physician satisfaction. MATERIALS AND METHODS The laboratory information system (LIS) was pro...

OBJECTIVE To determine women's (patients') experiences of intrauterine device (IUD) insertion under our current practice and the extent to which these agreed with the observations of the health professionals (providers) who had performed the IUD insertion procedures. METHOD Questionnaires were used to collect information on women's experiences of the IUD insertion procedure from both patients...

BACKGROUND Arformoterol, the (R,R) isomer of formoterol, is approved as an inhalation solution for the treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease. Multiple nebulizer systems are commercially available. Different nebulizers can differ significantly in drug output, which may impact drug delivery and clinical efficacy. This study compared the aerosol pr...

World trade talks have foundered recently, in part due to developing country demands that industrialised countries reduce their large farm support programmes to allow poor farmers in the global South to compete more fairly. But are subsidies really the problem? For some crops – most notably cotton and sugar – Northern subsidies clearly are a root cause of low international prices and unfair com...