نتایج جستجو برای: whole genome sequencing
تعداد نتایج: 563390 فیلتر نتایج به سال:
Assembling fragments randomly sampled from along a sequence is the basis of whole-genome shotgun sequencing, a technique used to map the DNA of the human and other genomes. We calculate the probability that a random sequence can be recovered from a collection of overlapping fragments. We provide an exact solution for an infinite alphabet and in the case of constant overlaps. For the general pro...
Example 1. In a genetic study, n = 2217 patients are recruited, among which 1127 have bladder cancer. After whole genome sequencing, p = 475290 single nucleatide polymorphisms (or SNPs, a possible variation of the DNA sequence at one location) are measured on each patient. We construct a matrix X = (Xij)1≤i≤n,1≤j≤p where Xij = 1 if the ith patient has a mutation at jth location and 0 otherwise....
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