background : the development of chemoresistance represents a major obstacle in the successful treatment of cancers such as non-hodgkin’s lymphoma (nhl). with the recognition of important roles for both p53 and its more recently described paralog p73 in mediating the activity of anti-cancer drugs, there has been increasing recognition that cellular resistance to anthracyclines could and does a...

introduction: analysis of smile is one of the esthetic evaluations in dentistry. in the present study, gla, lid, the long axis position and the oblique axial angle of each tooth were evaluated. materials and methods: in this cross-sectional analytical study, 80 subjects with properly-aligned teeth and healthy periodontium were selected. a digital camera was to take photos of lip areas in unifor...

objective(s): to investigate the efficacy of interleukin 11 (il-11) towards the high dose methotrexate (hdmtx)-concurrent rat small intestinal mucositis and its impacts on the proliferation of the human t-lymphoblastic leukemia (cem) cell line. materials and methods:95 wistar rats were randomly divided into five groups, the normal control group (a), the methotrexate (mtx) control group (b), the...

background and aims. orientation of the occlusal plane is one of the most important clinical procedures in prosthodontic rehabilitation of edentulous patients. the aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. materials and methods. fifty-three dental students (27 females and 26 males) wi...

background: the eradication of helicobacter pylori infection, commonly prevailing in the stomach, has been important since its introduction. adequate preparations should be made in finding alternatives when faced with first-line treatment failures. currently, ideal second-line treatments are indistinct and varied among countries as result of different antibiotic resistance patterns. we aimed to...

background and objective: the management of apoptotic cell death has been considered as a putative therapeutic strategy for cancer treatment. in the present study we investigated the putative pro-apoptotic effect of allicin, the main garlic organosulfur component with repeatedly claimed chemopreventive potency, on the human adenocarcinoma cell line ht29 as an apoptosis resistant cell line, in v...

the cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. this study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. human hgf1-pi53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/ml concentrations of the two bioactive...

ninety barley doubled haploid lines originated from crossing between six barley cultivars in cereal research department, seed and plant improvement institute, karaj, iran were evaluated for resistance to powdery mildew and some agronomic traits in field in 2007. six parent cultivars and a powdery mildew susceptible check cultivar, afzal were also included. sixty two doubled haploid lines showed...

purpose: to examine the effectiveness of group cognitive-behavioral therapy (cbt) based on schema on impulsiveness of substance abusers in karaj. materials and methods: this study was quasi-experimental with pre-test, post-test and control group. the statistical population of this study consisted of male substance abusers who referred to addiction treatment clinics of karaj in 2010. the sample ...