OBJECTIVES To determine the incidence of serious myelotoxicity from intravenous cyclophosphamide (IC) in systemic lupus erythematosus (SLE). METHODS In a retrospective study, white blood cell (WBC) counts with differential and platelet counts were determined in 92 SLE patients (96 courses) given 1623 doses of IC. RESULTS Only one patient developed a total leucocyte count <1000/mm3, one deve...

BACKGROUND Lower lung function is associated with an elevated systemic white cell count in men. However, these observations have not been demonstrated in a representative population that includes females and may be susceptible to confounding by recent airway infections or recent cigarette smoking. We tested the hypothesis that lung function is inversely associated with systemic white cell count...

Introduction: In the present study, the prophylactic effect of vitamin C, as a potent anti-oxidant, on tracheal responsiveness to methacholine and ovalbumin, bronchoalveolar lavage fluid white blood cell (WBC) count and differential count, and also lung pathology in chronic obstructive pulmonary disease (COPD) -guinea pigs (cigarette exposed guinea pigs) were examined. In addition, the relax...

Septic arthritis of the wrist can result in permanent damage to the joint, making timely diagnosis crucial to initiate empiric antibiotics and surgical intervention. Although septic arthritis is routinely included in the differential diagnosis of atraumatic wrist pain, the incidence is unknown. Unlike large joints, there is no consensus on cell count values considered pathognomonic for wrist se...

In the present study we investigated the potential of the Sysmex XE-2100 automated hematology analyzer as a screening device for bone marrow (BM) aspirates. We evaluated BM cellularity, white blood cell (WBC) differential count, immature granulocyte (IG) count, nucleated red blood cell (NRBC) count, granulocyte/erythroid (G/E) and myeloid/erythroid (M/E) ratio, and potential pathologyrelated sc...

A 34-year old man was admitted to hospital because of persistent fever and massive hepatosplenomegaly. His past history included excision of a melanoma of the right ear at the age of 16. A blood cell count showed anemia, thrombocytopenia and normal white blood cell (WBC) count with normal differential count. Neutrophils and monocytes containing black pigment were detected in the peripheral bloo...

OBJECTIVE To evaluate the antitumor activity of Manilkara zapota (M. zapota) L. stem bark against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. METHODS The in vivo antitumour activity of the ethyl acetate extract of stem bark of M. zapota L. (EASM) was evaluated at 50, 100 and 200 mg/kg bw against EAC using mean survival time. After administration of the extract of M. zapota, viable E...

Joint aspiration is a reliable tool for diagnosis of periprosthetic infection. There are different indications, techniques, and approaches for joint aspiration. We recommend that it be performed selectively when infection is suspected clinically. The specimens should be interpreted based on the results of the culture as well as the white cell count and differential. Specimen collection, transpo...