BACKGROUND Each year millions of Americans enroll in commercial and self-help weight loss programs. Health care providers and their obese patients know little about these programs because of the absence of systematic reviews. PURPOSE To describe the components, costs, and efficacy of the major commercial and organized self-help weight loss programs in the United States that provide structured...

BACKGROUND Ample evidence suggests a dose-response relationship between increasing weight and level of asthma risk or reduced asthma control. To establish reversibility, several randomized controlled trials (RCTs) have recently been published to investigate the impact of weight management on asthma. This systematic review synthesizes evidence from these RCTs on the effects of weight management ...

Nowadays, production systems seek to integrate production and maintenance activities. An effective maintenance plan can improve maintenance stability and system performance. Machines that stop for repairing operation impose a high cost on the system. On the other hand, there are always some intangible situations during a production process in which repairing activities can be carried out. If th...

This study investigated stigma directed at formerly obese persons who lost weight and became lean (through behavioral or surgical methods), or lost weight but remained obese, relative to weight-stable obese and weight-stable lean persons. This study also compared stigma directed at obese persons following exposure to descriptions of persons who lost weight vs. remained weight stable. In a betwe...

BACKGROUND When implemented at scale, the impact on health and health inequalities of public health interventions depends on who receives them in addition to intervention effectiveness. METHODS The MEND 7-13 (Mind, Exercise, Nutrition…Do it!) programme is a family-based weight management intervention for childhood overweight and obesity implemented at scale in the community. We compare the ch...

Broiler chicks were fed on chemically-defined crystalline amino acid diets containing graded levels of L-threonine (Thr) during the period 10-20 d post-hatching. Doses of Thr represented 5,10,15,40, 55, 70 and 95 % of its ideal level for maximal weight gain and feed efficiency. Other amino acids were maintained at minimized excess levels that were 15 % (of ideal) above the various doses of Thr....

Broiler chicks were fed on chemically-defined crystalline amino acid diets containing graded levels of L-threonine (Thr) during the period 10-20 d post-hatching. Doses of Thr represented 5, 10, 15, 40, 55, 70 and 95% of its ideal level for maximal weight gain and feed efficiency. Other amino acids were maintained at minimized excess levels that were 15% (of ideal) above the various doses of Thr...

OBJECTIVE Our objective was to assess the efficacy and safety of sibutramine with a low-calorie diet (LCD) and commercial meal-replacement product in achieving weight loss and weight-loss maintenance in obese patients. RESEARCH METHODS AND PROCEDURES Eight U.S. centers recruited 148 obese patients for a 3-month comprehensive weight-loss therapy (Phase I) comprising daily sibutramine 10 mg + L...

BACKGROUND We recently demonstrated leucine to modulate energy partitioning between adipose tissue and muscle. Further, leucine exhibits a synergy with B6, resulting in reduced adipocyte lipid storage coupled with increased muscle fat oxidation. Accordingly, a nutraceutical (NuShape™) containing 2.25 g leucine and 30 mg B6 increased fat oxidation by >30 g/day in a 28-day randomized controlled t...