The present study investigated the effects of co-administration of aspirin, metformin, atorvastatin and captopril on serum lipid profile and oxidative stress in the heart and kidney of streptozotocin-induced diabetic rats. In this study, rats were randomly divided into the following eleven groups: control (Cont.), and diabetic (D), as well as 9 groups that were treated with metformin (M, 300 mg...

The framework of hybrid control systems can be used t.0 examine digital control systems. This paper shows how digital control systems can be modeled as hybrid cont,rol systems. A technique for designing interfaces for hybrid control systems is presented. An example is employed to demonstrate how this technique, as well as a DES cont,roller design methodology developed earlier, can be applied to...

Rho-kinase-mediated vasoconstriction and endothelial dysfunction are considered two primary instigators of pulmonary arterial hypertension (PAH). However, their contribution to the adverse changes in pulmonary blood flow distribution associated with PAH has not been addressed. This study utilizes synchrotron radiation microangiography to assess the specific role, and contribution of, Rho-kinase...

In recent years erotic acid (uracil-4-carboxylic acid) has been found to be essential for the growth of some microorganisms;l some pyrimidine-requiring Neurospora mutants were found to grow equally well with uracil and erotic acid2 and some mutants have been found to produce erotic acid.3 It has been suggested that erotic acid is a by-product in the biosynthesis of pyrimidines in Neurospora.s I...

purpose: obesity is one of the most common problems in the world. imbalance between energy consumption and expenditure is a main factor in weight disorder. exercise helps losing weight by increasing energy expenditure and modulation of the energy intake. the present study examined protective effects of daily moderate aerobic exercise on preventing weight gain in high fat diet rats. materials an...