We examine the effect of individual psychological differences on network structures, proposing several hypotheses about how individual differences might predispose actors to structure their social environment by seeking network closure or by sustaining structural holes. We introduce a new triad census method to examine personal networks of strong and weak ties. For 125 egocentric networks we co...

Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design.

liquid-liquid equilibrium data for the (water + lactic acid + 2-ethy-1-hexanol) ternary system in t=298.2k and p=1atm were determined and tie- lines related to equilibrium data has been drawn in the phases diagram . the reliability of the experimental tie-line data for this system was as confirmed by using the hand and othmer –tobias correlations. the tie-line data were correlated by means of t...

Diabetes is associated with impairment of angiogenesis such as reduction of myocardial capillary formation. Our previous studies demonstrate that disruption of Angiopoietin-1 (Ang-1)/Tie-2 signaling pathway contributes to the diabetes-associated impairment of angiogenesis. Protein tyrosine phosphatase (PTP) has a critical role in the regulation of insulin signal by inhibition of tyrosine kinase...

BACKGROUND Curative resection of sigmoid colon and rectal cancer includes "high tie" of the inferior mesenteric artery (IMA). However, IMA ligation compromises blood flow to the anastomosis, which may increase the leakage rate, and it is unclear whether this confers a survival advantage. Accordingly, the IMA may be ligated at a point just below the origin of the left colic artery (LCA) "low tie...

We extend the existing enumeration of neck tie knots to include tie knots with a textured front, tied with the narrow end of a tie. These tie knots have gained popularity in recent years, based on reconstructions of a costume detail from The Matrix Reloaded, and are explicitly ruled out in the enumeration by Fink and Mao (2000). We show that the relaxed tie knot description language that compre...

Previous studies have investigated alliance networks primarily from two alternative views, a relational view that focuses on the “strength of strong/weak ties,” or a structural view that refers to a firm’s position and structural embeddedness. We posit a firm’s network architecture, i.e., the portfolio of strong/weak ties, influences its conduct and performance. From a resource-based view, the ...

when power systems are expanded and connected together with weak tie lines, the low-frequency oscillations are increased and the stability margin of the power system decreases. therefore, when designing the transmission system to be used, it is necessary to maintain the dynamic stability of the power system, and to make sure to have the most possible stability margin. sssc is a facts device con...

A novel method we refer to as the tie-line field (TLF) method has been developed to globally determine the tie lines of any three-component two-phase coexistence region by fitting electron-spin resonance (ESR) spectra obtained from compositions on the coexistence curve and within the coexistence region. The TLF method is illustrated by applying it to the liquid-ordered (Lo) and liquid-disordere...

Background: Wearing a neck-tie is necessary for bankers and office workers as per requirement of their job. It to know about the impact regular tie-wearing. Objective: To find out association neck pain in tie wearing non-tie computer users. Methodology: was comparative cross sectional survey, conducted different banks offices Lahore, sample size 200. Group A: consists 100 regularly tie-wearing ...