Purpose: Women who are surgically treated for vulvar cancer often have complications leading to substantial patient morbidity. Post-surgical complications could be minimized by the identification of pre-surgical risks for complications and by planned post-surgical interventions. Therefore, the aim of this study was to develop a clinical care algorithm for vulvar cancer to assess risk for compli...

Human papilloma virus (HPV) is considered to be responsible for a large part of vaginal and vulvar carcinomas, and the p53 codon 72 polymorphism has been implicated in susceptibility to cancer induced by this virus, but with contradicting results. In this study, we have investigated the prognostic value of the codon 72 polymorphism by real-time PCR (qPCR) in two cohorts of vaginal (n = 66) and ...

The article presents a clinical case of perineal defect reconstruction using VRAM flap in patient with vulvar cancer. Stepwise surgical treatment method is described. A multidisciplinary meeting allows to realize plan help for such patients the goal treating oncological process and its complications. We have proposed variant through transfer vertical rectus abdominis musculocutaneous vascular p...

OBJECTIVES The SLN-procedure has been introduced in vulvar cancer treatment to reduce morbidity and thereby improve quality of life. Aim of this study was to compare quality of life in vulvar cancer patients who were treated with a SLN-procedure only to those who underwent inguinofemoral lymphadenectomy. Moreover, it was evaluated what patients would advise relatives on the application of the S...

This review aims to sketch current scenario of cancers in female reproductive system such as cancer in uterus, ovary, cervix, vagina, vulvar, fallopian tube along with hydatidiform and their treatment strategies.

Cutaneous metastasis is considered as a hazardous condition depending on the mean survival around 9 months, which usually originates from cancers of the breast, lung, ovary, colon, and rarely from the cervix. The crucial prognostic factor of cutaneous metastasis depends on the period between the primary malignancy and cutaneous metastasis. We report two cases of the unusual presentation of squa...

•Seventy- 5% of vulvar cancer cases present with advance disease.•Definitive radiotherapy/chemoradiation is the main stay of treatment.•One third of patients default treatment.•Five year survival following radiotherapy was 36.7%.

Surgery on vulvar malignancies has become more conservative over the past several decades. A radical vulvectomy with removal of bilateral inguinal lymph nodes en bloc, a mutilating procedure fraught with high complication rates still performed in the 1980s, has become a rarity in today’s practice. This may be partially due to the fact that tumors tend to be diagnosed at earlier stages, thanks t...

  Fibroadenoma of the vulva is an uncommon lesion. It has been suggested that they originate from vulvar mammary like other glands. A few examples of benign and malignant vulvar tumors arising from such glands have been reported. A 32-year-old woman was referred with a subcutaneous mass at the vulva. The patient treated by simple excisional surgery with adequate peripheral margin. Histologic...