نتایج جستجو برای: voxel based morphometry

تعداد نتایج: 2944555  

Journal: :Twin research and human genetics : the official journal of the International Society for Twin Studies 2012
Jessica A Turner Vince D Calhoun Andrew Michael Theo G M van Erp Stefan Ehrlich Judith M Segall Randy L Gollub John Csernansky Steven G Potkin Beng-Choon Ho Juan Bustillo S Charles Schulz FBIRN Lei Wang

Structural brain measures are employed as endophenotypes in the search for schizophrenia susceptibility genes. We analyzed two independent structural imaging datasets with voxel-based morphometry and with source-based morphometry, a multivariate, independent components analysis, to determine the stability and heritability of regional gray matter concentration abnormalities in schizophrenia. The...

2017
Vanja Kljajevic

There is currently little understanding on whether significant word retrieval difficulties appear during midlife and if so, whether they relate to decrease in grey matter (GM) density that accompanies aging. To answer this question, we studied retrieval of proper names in 125 cognitively healthy middle-aged persons (49.7, ±3.2) comparing their performance on a tip-of-the-tongue (TOT) task with ...

2004
Andrea Mechelli Cathy J. Price Karl J. Friston John Ashburner

In recent years, a whole-brain unbiased objective technique, known as voxel-based morphometry (VBM), has been developed to characterise brain differences in vivo using structural magnetic resonance images. The present review provides a brief description of VBM and then focuses on exemplar applications in healthy and diseased subjects. The procedure involves normalising high-resolution structura...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2005
C Pennanen C Testa M P Laakso M Hallikainen E-L Helkala T Hänninen M Kivipelto M Könönen A Nissinen S Tervo M Vanhanen R Vanninen G B Frisoni H Soininen

BACKGROUND Mild cognitive impairment (MCI) is the most widely used concept in classifying cognitive impairment in the elderly who do not fulfil the criteria for dementia. MCI is considered to confer an increased risk of progressing to dementia and most often Alzheimer's disease (AD). Various approaches such as imaging of the brain have been applied to predict the conversion of MCI to dementia. ...

2012
Daniel-Paolo Streitbürger Harald E. Möller Marc Tittgemeyer Margret Hund-Georgiadis Matthias L. Schroeter Karsten Mueller

Dehydration can affect the volume of brain structures, which might imply a confound in volumetric and morphometric studies of normal or diseased brain. Six young, healthy volunteers were repeatedly investigated using three-dimensional T(1)-weighted magnetic resonance imaging during states of normal hydration, hyperhydration, and dehydration to assess volume changes in gray matter (GM), white ma...

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