purpose: to evaluate the safety of different doses of intravitreal bevacizumab in rabbit eyes. methods: twelve eyes of 6 rabbits underwent intravitreal injection of 5, 7.5 and 10 mg of bevacizumab. in each rabbit, one eye was considered for bevacizumab injection and the fellow eye served for either placebo injection or observation. all eyes were examined before and 1, 2, 3, 7, 14 and 28 days af...

BACKGROUND Herpetic necrotizing retinitis is a well-recognized entity. A few cases of herpetic non-necrotizing retinitis were previously reported. FINDINGS We retrospectively report two cases of herpetic non-necrotizing retinopathy with a long follow-up. A 19-year-old woman presented with a bilateral diffuse occlusive retinal vasculitis, peripheral neovascularization, and no signs of retinal ...

BACKGROUND Endogenous endophthalmitis, extra-hepatic metastasis from liver abscess with diabetes mellitus, could lead to a devastating outcome without a prompt and appropriate management. We report a case of metastatic endophthalmitis combined with subretinal abscess with successful visual outcome after treatment. CASE PRESENTATION A 56-year-old male patient with diabetes mellitus under poor ...

AIM To investigate whether presumed ocular histoplasmosis syndrome in the Netherlands is caused by Histoplasma capsulatum and whether other risk factors might play a role in the pathogenesis of this syndrome. METHODS 23 patients were clinically diagnosed as having presumed ocular histoplasmosis syndrome based on the following criteria: peripapillary atrophy, punched out lesions, a macular dis...

A 28 year-old man presented with sudden visual loss in his left eye. Best-corrected visual acuity was 20/20 in the right eye and 20/400 in the left eye. Fundus examination showed a whitish retinal lesion of the superotemporal quadrant involving the supero-temporal retinal vein branch with mild vitritis. Fluorescein angiography confirmed active retinochoroidal inflammation (black arrow) with del...

BACKGROUND Intravitreal injection of triamcinolone has been advocated to treat exudative macular diseases such as macular edema and choroidal neovascularization. OBJECTIVE To describe 7 patients who developed a clinical picture simulating endophthalmitis after intravitreal triamcinolone injection. METHODS Intravitreal triamcinolone injections were performed to treat refractory cystoid macul...

IMPORTANCE This is a notice to ophthalmologists performing intravitreal injections of triamcinolone or other medications of the risk for endophthalmitis caused by Bipolaris hawaiiensis-contaminated medications. OBSERVATIONS Histopathologic review of 5 eyes from a series of 17 treated with intravitreal triamcinolone for retinal vascular disease and diabetes mellitus over 1 year from 1 lot prep...

BACKGROUND Live intraocular nematode is a rare occurrence. Nematode can migrate actively within the eye, creating visual symptoms and damaging ocular tissue. CASE PRESENTATION A 26-year old man presented with painless reduced vision of the left eye for one week duration. It was associated with floaters. Visual acuity on the left eye was hand movement. Anterior segment examination was normal w...

Marfan’s syndrome (MFS) is an autosomal dominant connective tissue disorder involving the cardiovascular, skeletal and ocular systems.Cardinal manifestations include aortic aneurysm and dissection, ocular lens dislocation and long bone overgrowth. The most common cause of ectopia lentis is trauma, which accounts for nearly onehalf of all cases of lens dislocation. A forward dislocation of the l...

purpose: to determine the prevalence of ocular involvement in patients with tuberculosis (tb) infection. methods: all patients with a new diagnosis of tb who were referred to zahedan tuberculosis center underwent a complete ophthalmic examination. any cases of known ophthalmic disease or previous ocular involvement were excluded from the study. prevalence of ocular involvement with 95% confiden...