OBJECTIVE To investigate the expression of the profibrotic connective tissue growth factor (CTGF) in relation to severity of intraocular fibrosis and neovascularization in human vitreoretinal disorders for the identification of potential therapeutic targets to prevent fibrosis. METHODS Concentrations of CTGF were measured by enzyme-linked immunosorbent assay in 119 vitreous samples from patie...

AIM To evaluate the anterior segment complications of phacovitrectomy and foldable intraocular lens (IOL) implantation in eyes with significant cataract and co-existing vitreoretinal diseases. METHODS This retrospective study was consisted of 285 eyes of 238 patients with various vitreoretinal abnormalities and visually significant cataracts. Vitreoretinal surgery was combined with phacoemuls...

BACKGROUND To study the effect of retinal/ vitreoretinal surgeries on corneal elevations. METHODS Patients who underwent retinal/ vitreoretinal surgeries were divided into 3 groups. Scleral buckling was performed in 11 eyes (Group 1). In 8 (25%) eyes, vitreoretinal surgery was performed along with scleral buckling (Group 2). In 12 eyes, pars plana vitrectomy was performed for vitreous hemorrh...

AIM Posterior vitreous detachment (PVD) is a physiological phenomenon due to aging characterized by separation of the vitreous cortex from the retina and may induce a variety of pathological events at the vitreoretinal junction. The aim of this study is to highlight in vivo anatomical and functional changes in early stages of PVD allowing the correct treatment. MATERIAL AND METHODS Non-consec...

The literature review focuses on penetrating macular holes, a topical issue in vitreoretinal surgery. Multiple theories and the modern view pathogenetic mechanisms hole formation are presented. A classification of holes is proposed.

The vitreous body is bounded posteriorly by the retina and is adherent to it. Abnormalities in the adhesion between the vitreous and the macula, or vitreoretinal interface, are involved in the pathogenesis of several macular conditions. Optical coherence tomography is a noninvasive in vivo ophthalmic imaging technique, which allows for a better understanding and improved diagnosis of disease pr...

Pars plana vitrectomy (PPV) was introduced almost 40 years ago. 1 In the 1980s and 1990s, three-port PPV with 20-gauge (G) instruments was the norm. In 2002, 25-gauge transconjunctival sutureless vitrectomy (TSV) was introduced.2,3 This system permits threeport PPV using microcannulas, trocars, and 25-G instrumentation without requiring sutures to close the sclerotomies. Subsequently, a similar...