Infection of domestic cats with Feline immunodeficiency virus (FIV) results in a fatal immunodeficiency disease, similar to Human immunodeficiency virus 1 (HIV-1) in humans. Elevated plasma viral loads in domestic cats are correlated to decreased survival time and disease progression. However, FIV is also maintained as an apathogenic infection in other members of the family Felidae including co...

The objective of the study : to investigate diagnostics, course and outcomes COVID-19 in children adolescents with tuberculosis relation epidemic control activities. Subjects Methods during pandemic coronavirus infection (the first second waves), 83 patients aged 2 17 years (41 42 adolescents) were followed up. 62 (74.7%) got infected novel among 82 treated at clinic over this time. Results. ha...

Hantaviruses are RNA viruses with known epidemic threat and potential for emergence. Several rodent-borne hantaviruses cause zoonoses accompanied by severe illness death. However, assessments of zoonotic risk the development countermeasures challenged our limited knowledge molecular mechanisms hantavirus infection, including identities cell entry receptors their roles in influencing viral host ...

The disease COVID-19 caused by SARS-CoV-2 is the third highly infectious human Coronavirus epidemic in 21s⁢t century due to its high transmission rate and quick evolution of pathogenicity. Genomic studies indicate that it zoonotic from bats. has led significant loss lives a tremendous economic decline world. Generally, population at risk fatal outcome are elderly those who debilitated or immune...

BACKGROUND Classic modeling of sexually transmitted diseases has focused on modeling behavioral heterogeneity and designing epidemic control strategies targeted at behavioral core groups. METHODS We analyzed a new mathematical model of herpes simplex virus type 2 (HSV-2) epidemics that includes virological core groups (i.e., groups of individuals with high rates of viral reactivation) and sug...

The objective: to determine main directions for improving the epidemiological control over socially important infectious diseases (tuberculosis, HIV infection, viral hepatitis B and C) based on study of epidemic signs its determinants from 2010 2021. Subjects Methods. Rosstat Forms no. 8, 33, 61, 4, 2, 12, C51 were studied. Epidemiological statistical analysis content publications applied. Calc...

Protease 2A (2Apro) of coxsackievirus B3 (CVB3) plays a major role in viral replication. In case of infection, viral proteins are being synthesized from viral mRNA using host biosynthesis machinery. 2Apro of virus, after being synthesized, exhibits two critical functions, cleavage of viral proteins and breaking eukaryotic initiation factor 4G. The enzyme plays an essential role in viral replic...

Because of its relevance to everyday life, the spreading of viral infections has been of central interest in a variety of scientific communities involved in fighting, preventing and theoretically interpreting epidemic processes. Recent large scale observations have resulted in major discoveries concerning the overall features of the spreading process in systems with highly mobile susceptible un...

Most current candidate HIV vaccines seem to produce little protection against infection, but reduce viral load and slow the decline in CD4 lymphocyte numbers. Such disease-modifying vaccines could potentially provide important population-level benefits by reducing transmission, but could possibly also increase transmission. We address the following question: could disease-modifying HIV vaccines...

BACKGROUND In the year 2005, an epidemic of Japanese encephalitis (JE) occurred in the northern states of India. The present study was planned to reconfirm the circulation of JE in the area and to assess the trend of the disease to slow down the burden of JE. METHODOLOGY Surveillance was conducted to identify patients with acute encephalitis. Blood and cerebrospinal fluid specimens from suspe...