Virus Infection Testing Monina Klevens, DDS, MPH; Carmen Pugh, MT; John Ward, MD; Daulati Thakare; Scott Holmberg, MD, MPH; Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA; National Office of Quality, LabCorp, Burlington, NC; Division of Viral Hepatitis, Centers for Disease Control and Prevention/NCHHSTP, Atlanta, GA; Division of Viral Hepatitis, National Ce...

background although certain hbv mutations are known to affect the expression of hepatitis e antigen, their association with hbv viral level or clinical outcomes is less clear. objectives we evaluated associations between different mutations in the basal core promoter (bcp) and pre-core (pc) regions of hbv genome and subsequent changes in hbv viral dna level over seven years in a population of u...

BACKGROUND AND OBJECTIVES Cytomegalovirus (CMV) disease remains an important complication of allogeneic stem cell transplantation (SCT). We studied viral load kinetics and correlated the viral load and other transplant factors with the development of CMV disease. DESIGN AND METHODS We studied 162 consecutive patients who were CMV seropositive or had CMV seropositive donors. Quantification of ...

conclusions the newly developed simple indirect elisa showed high sensitivity and specificity with respect to vnt. developing such a simple, sensitive, and specific elisa which is much less expensive than the available commercial elisa kits can improve the detection of bvdv infections, help to eliminate the disease from herds, and decrease economic losses caused by this disease. background bovi...

Newcastle disease is one of the main concerns of poultry farmers. Detection of virulent strains of Newcastle disease virus (NDV) has a great impact on control measures against the disease. In this study RT-PCR was optimized in high sensitivity in order to differentiate the virulent from non-virulent NDV isolates directly in tissue homogenates. The vaccinal NDV strain and known field isolates we...

Infectious diseases can impact the physiological performance of individuals, including their mobility, visual acuity, behavior and tolerance and ability to effectively respond to additional stressors. These physiological effects can influence competitiveness, social hierarchy, habitat usage, migratory behavior and risk to predation, and in some circumstances, viability of populations. While the...

waterborne epidemics of viral diseases have occurred and been reported over the years, and isolation of viruses from water of different sources has been made possible by different methods of concentration. it is now believed that bacterial parameters of water purity may not provide an adequate index as to the safety from a virological point of view. in this study eight samples from four main te...

Crimean-Congo Hemorrhagic Fever is a fatal viral disease that occurs in some parts of Africa, Asia, Eastern Europe and the Middle-East. Primarily it is a zoonosis but can be seen sporadically in humans. Recently outbreaks have been reported from Pakistan, Afghanistan, Saudi Arabia, United Arab Emirates and Iran. In this retrospective study, we evaluated the efficacy of oral Ribavirin in the...