OBJECTIVES Newborn screening for cystic fibrosis (CF) facilitates early diagnosis and genetic counselling for parents of affected infants. Many parents elect to use prenatal testing for subsequent pregnancies, and this may affect the prevalence of CF. The aim of this study was to assess the evidence for changes in the live-birth prevalence of CF since the introduction of newborn screening for C...

We construct quasiconformal mappings in Euclidean spaces by integration of a discontinuous kernel against doubling measures with suitable decay. The differentials of mappings that arise in this way satisfy an isotropic form of the doubling condition. We prove that this isotropic doubling condition is satisfied by the distance functions of certain fractal sets. Finally, we construct an isotropic...

The authors present the central capacity sharing (CCS) model and derive equations describing its behaviors to explain results from dual-task situations. The predictions of the CCS model are contrasted with those of the central bottleneck model. The CCS model predicts all of the hallmark effects of the psychological refractory period (PRP) pardigm: -1 slope of the PRP effect at short stimulus on...

Stimuli that are clearly positive or negative (hence valence-laden stimuli) have the potential to interrupt unrelated task processing. A typical example is the emotional Stroop effect (ESE) in which responding to a certain task feature (e.g., color) is delayed by the presentation of task-irrelevant valent stimuli (e.g., negative pictures) compared to valence-neutral stimuli. Here we scrutinize ...

Video games have become important but understudied narrative media, which link into as well perpetuate popular forms of cultural memory. They evoke and mediate space (or the illusion thereof) in unique ways, literally putting play Doreen Massey’s theory being produced through a multiplicity trajectories. I examine how Assassins Creed: Syndicate The Order 1886 (both 2015) configure neo-Victorian...

Taking present-day research into so-called new momism and intense mothering as a starting point, this article argues that the current mothering discourse, rather than articulating a new phenomenon, perpetuates a regulative discourse developed in the nineteenth century, in advice books written by medical doctors for pregnant women and new mothers. Both the Victorian and the present-day texts pla...

The guiding thesis of Angus Hawkins’s Victorian Political Culture: ‘Habits of Heart & Mind’, is the beguilingly simple one that Victorian political values rested on the Shibboleths of history, morality and community, and that the differing political outlooks of radicals, Liberals, Conservatives and even socialists throughout the century can be traced back to their very different interpretations...

Abstract. Given a doubling measure μ on R, it is a classical result of harmonic analysis that Calderón-Zygmund operators which are bounded in L(μ) are also of weak type (1, 1). Recently it has been shown that the same result holds if one substitutes the doubling condition on μ by a mild growth condition on μ. In this paper another proof of this result is given. The proof is very close in spirit...

A change in subtask order in the psychological refractory period (PRP) paradigm increases the effect of stimulus onset asynchrony (SOA) on the second response. We used a paradigm with cued, randomly determined subtask order to test the hypothesis that this SOA by order switch overadditivity reflects order control, via "copying" stimulus order. In Experiments 1a and 1b, overadditivity was eviden...

For the purposes of funding and policy development, the Victorian Department of Human Services expects Victorian health care institutions to capture patient data at all levels. These data can be extracted from hospital information systems and potentially offer a business role within a health service organisation. However, there are many issues to be addressed at the organisational level in orde...