Vinblastine is an important anticancer agent known to diminish microtubule assembly. Ab initio calculations are applied to examine the structural properties and different energies of vinblastine-tubulin complex in different dielectric constants and temperatures. The aims of this work are discovery the best optimized structure and thermodynamic properties of vinblastine-tubulin complex ...

ALTHOUGH MANY STUDIES HAVE SHOWN an association between operating heavy construction equipment and symptoms of musculoskeletal disorders (MSDs), little research has been performed that systematically characterizes the exposure of operating engineers to ergonomic hazards. This study evaluated: 1) vibration at the seat/operator interface; 2) transmissibility of vibration in the Z-axis; 3) psy-cho...

Fundamental frequency of vocal fold vibration (F0) and acoustic intensity are correlated for physiological and linguistic reasons. Previous studies have established that aerodynamic factors and vocal fold control mechanisms are partly responsible for the correlation. Intonational accents are also a source of co-variation of F0 and intensity. This paper addresses the question of whether these ph...

In our study we examined postural performance of young healthy persons (HY), elderly healthy persons (HE), and elderly persons at high risk of falling (FR). Anterio-posterior (AP) and medio-lateral (ML) ankle and hip angular deviations, as well as linear displacements of the center of mass (COM) were assessed in persons standing with eyes either open or closed, while none, and 40 and 30 Hz vibr...

Nonlinear dynamic analyses are performed to compute the maximum relative input energy per unit mass for 21 multi-degree-of-freedom systems (MDOF) with preselected target fundamental periods of vibration ranging from 0.2 to 4.0 s and 6 target inter-story ductility demands of 1, 2, 3, 4, 6, 8 subjected to 40 the earthquake ground motions. The efficiency of the several intensity measures as an ind...

A hand-arm vibration syndrome occurs in some workers who use hand held vibrating tools. It is recognised to consist of white fingers, diffusely distributed finger neuropathy, pain in the arm and hand, and a small excess risk of osteoarthrosis from percussion to the wrist and elbow. Carpal tunnel syndrome is mainly due to ergonomic factors other than vibration, but certain factors related to vib...

Railway traffic induced vibrations in dwellings often cause irritation or disturb the inhabitants. Mitigation has been performed, and measurements prove their effectiveness. The effect of vibration countermeasures on the quality of living however has not been studied earlier. The objective of the study was to evaluate the effects of vibration mitigation compared to the increase of inhabitant sa...