نتایج جستجو برای: vervet monkeys

تعداد نتایج: 22495  

2009
Jörn E. Schmitz Roland C. Zahn Charles R. Brown Melisa D. Rett Ming Li Haili Tang Sarah Pryputniewicz Russell A. Byrum Amitinder Kaur David C. Montefiori Jonathan S. Allan Simoy Goldstein Vanessa M. Hirsch

African green monkeys (AGM) and other natural hosts for simian immunodeficiency virus (SIV) do not develop an AIDS-like disease following SIV infection. To evaluate differences in the role of SIV-specific adaptive immune responses between natural and nonnatural hosts, we used SIV(agmVer90) to infect vervet AGM and pigtailed macaques (PTM). This infection results in robust viral replication in b...

2012
Joshua Muli Mutiso John Chege Macharia Evans Taracha Michael Muita Gicheru

In a previous immunogenicity and efficacy study in mice, montanide ISA 720 (MISA) was indicated to be a better adjuvant than bacillus calmette guerin vaccine (BCG) for a Leishmania vaccine. In the present study, we report the safety, immunogenicity and efficacy of Leishmania donovani (L. donovani) sonicated antigen delivered with alum-BCG (AlBCG), MISA or monophosphoryl lipid A (MPLA) in vervet...

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