Plants have been used as folkloric sources of medicinal agents since the beginning of mankind. As the age of modern medicine, single pure drugs emerged, and plant-derived active principles, their semi-synthetic and synthetic analogs have served as a major route to new pharmaceuticals. Since 1961, plant-derived compounds have been approved for use as anticancer drugs: vinblastine (Velban®), vinc...

Indole acetic acid (IAA) is a plant growth-promoting hormone used in agriculture; therefore, its continuous production is of paramount importance. IAA-producing eight bacteria were isolated from the rhizosphere of Verbascum vulcanicum. Among them, Arthrobacter agilis A17 gave maximum IAA production (75 mg/L) and this strain was used to immobilization studies. The A. agilis A17 cells were immobi...

Orange mullein is a biennial plant belonging to the figwort (Scrophulariaceae) family. The vivid yellow flowers are arranged in spikes located on top of stem. It drought and cold-tolerant requiring much sunlight that grows pastures, roadsides, dry weed associations. aim this study was assess effect different solvents (water, 70% acetone, methanol, ethanol) assessment antioxidant capacity leaves...

Methanol, acetone and ethyl acetate extracts obtained from Verbascum pinnatifidum Vahl. V. antinori Boiss. et Heldr were investigated for their bioactive composition, antimicrobial antibiofilm activity. Antimicrobial activity was determined with Escherichia coli NRRL B-3704, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris 13315, Acinetobacter baumanii 19606), Bacillus subtilis 6633, Staphyl...

The multiresistance of bacteria to antibiotics, as well as the lack of new antibiotics on the market encouraged the reasearch of antibacterial activity of non-antibiotic substances including plant extracts. During the previous decades, it has been proven that extracts of certain plants have a strong antibacterial activity, but their clinical use was limited due to the presence of organic solven...

In this study, heavy metal content (Cu, Fe, Mn, Ni, Pb, Zn) was determined in soils and different organs of Verbascum olympicum Boiss. This species is endemic to Uludağ and spreads on destroyed areas such as: roadsides, developed building areas, ski lift stations and sheep folds. Soils and different organs (roots, stems, leaves and flowers) of plant samples were analyzed using an atomic absorpt...