We report a case of concomitant EML4-ALK and TPM3-ROS1 fusion in non-small cell lung cancer (NSCLC) in a 47-year-old Chinese man and review the clinical characteristics of this type double of fusion. The patient presented with a local tumor of the left upper lobe and underwent thoracoscopy. Postoperative surgical pathologic staging revealed T1a N0 M0 stage IA. Histological examination of the tu...

PURPOSE This study aimed to determine the relationship between ALK status and lung adenocarcinoma subtypes, according to the IALSC/ATS/ERS classification in Chinese patients. METHODS A reclassification of 2299 surgically resected lung adenocarcinomas was performed, and ALK status was detected by immunohistochemistry (Ventana Medical Systems) in Shanghai Chest Hospital. RESULTS ALK rearrange...