Marjolin’s ulcer is an uncommon malignant condition related to non-healing wounds, more often of burn injuries. Our aim is increase the suspicion index of primary care workers about the risk of squamous cell carcinoma in skin chronic ulcers or scar tissue, mainly in extremities. We report a Marjolin’s ulcer associated with traumatic chronic ulcer in the leg of a 73-year-old white female. Histol...

Leg ulcer is a leading cause of morbidity among older subjects, especially women in the Western world. About 400 years BC, Hippocrates wrote, "In case of an ulcer, it is not expedient to stand, especially if the ulcer be situated on the leg". Hippocrates himself had a leg ulcer. The best treatment of any leg ulcer depends upon the accurate diagnosis and the underlying aetiology. The majority of...

OBJECTIVE This study assessed the effectiveness of polarised, polychromatic, non-coherent light therapy in the treatment of venous leg ulcers. Investigators in previous studies have advocated the use of light as an adjunct to other proven therapies or on its own. METHOD This was a pilot prospective case-series study. We enrolled 25 patients with venous leg ulcers. All were treated with light ...

INTRODUCTION Venous leg ulceration is associated with pain and poor health-related quality of life (HRQL). The purpose of this study was to identify demographic and clinical characteristics associated with pain and decreased HRQL in patients with active venous ulcers. METHODS Baseline data were combined from two trials that took place between 2001 and 2007 (n = 564). Pain was measured using t...

Dear Editors, Vascular leg ulcers are a very common disease with a complicated management, a significant sanitary expense, as well as a significant repercussion in patient’s quality of life. An appropriate analgesic control is essential for the management of this condition. Themost commonly used therapeutic options to treat the pain are oral analgesics (Non-Steroidal Anti-Inflammatory Drugs (NS...

Review Article Current understanding on venous leg ulcer U Alok*, P Bhardwaj, A Singh, JJ Cherian TATA Consultancies Services, Regulatory Medical Writing, Wellspring, Vikhroli, Mumbai, Maharashtra, India Quintiles Research India Pvt. Ltd, Bangalore, Karnataka, India Bharati Vidyapeeth University Medical College, Pune, Maharashtra, India Government Medical College, Department of Pharmacology, Th...

Dear Editor, The problem of whether some systemic pharmacological adjuncts confer significant benefit to the healing process of chronic venous ulcers has been widely discussed in several narrative surveys and in a number of consensus conferences, systematic reviews and meta-analyses. The most relevant are the extensive and detailed survey by Nelson 1 and the multi-society consensus on the manag...

The effects of intermittent pneumatic compression on the healing rates of ulcers in patients with chronic venous insufficiency were examined in a prospective, controlled study of 22 patients. Patients were randomly assigned to the experimental or the control group. Both groups received local wound care followed by application of an Unna boot. In addition, subjects in the experimental group rece...

OBJECTIVE Deep venous stenting has become the primary treatment option for chronic venous obstructive disease, both for iliac vein compression and post-thrombotic venous lesions. Until recently, only stents aimed at arterial pathology were used, because no dedicated venous stents were available. However, three such stents have now become available. These venous stents are characterized by incre...

Chronic inferior vena cava and iliac vein occlusion, caused by long-term of deep venous thrombosis, will lead to swelling of the limbs, venous claudication and intractable ulcer. However, conservative treatment is often ineffective for vein occlusion. With the development of interventional techniques, endovascular therapy has become the first choice for the treatment of vein occlusion with high...