previous studies have demonstrated that vascular endothelial growth factor (vegf) can trigger angiogenesis as well as inflammation through binding to its membranous receptor-1 on endothelial and inflammatory cells. we aimed to correlate the circulatory number of cells expressing such receptor as well as the serum level of vegf and the soluble form of its receptor-1 (svegfr1) to the severity of ...

background: the effects of the vascular endothelial growth factor (vegf) gene ?2578c/a polymorphism on colorectal cancer (crc) risk have been investigated in some studies; however, the results of these studies were conflicting and ambiguous. therefore, we aimed to do a meta-analysis to investigate the association of vegf ?2578c/a polymorphisms with crc risk from all eligible case-control studie...

background: establishment of viable pregnancy requires embryo implantation and placentation. ectopic pregnancy (ep) is a pregnancy complication which occurs when an embryo implants outside of the uterine cavity, most often in a fallopian tube. on the other hand, an important aspect of successful implantation is angiogenesis. vascular endothelial growth factor (vegf) is a potent angiogenic facto...

tumor cells are dependent on angiogenesis to obtain oxygen and nutrients and also development of their new vascular network. vegf as an important stimulator of angiogenesis and endostatin as an inhibitor play a fundamental role in this process. this study was designed to investigate the effect of six weeks of resistance training on tumor tissue vegf andendostatin in mice with breast cancer. for...

background: pancreatic islet transplantation has emerged as a promising treatment for type i diabetes. however, its efficacy is severely hampered due to poor islet engraftment and revascularization, which have been resulted to partially loss of transplanted islets. it has been shown that local delivery of vascular endothelial growth factor (vegf) could accelerate transplanted islet revasculariz...