Sphingobium sp. SYK-6 is a soil bacterium boasting a well-studied ligninolytic pathway and the potential for development into a microbial chassis for lignin valorization. An improved understanding of its metabolism will help researchers in the engineering of SYK-6 for the production of value-added chemicals through lignin valorization. We used 13C-fingerprinting, 13C metabolic flux analysis (13...

The effects of some imine and amine derivatives of vanillin on the respiration rate of mouse mammary adenocarcinoma TA3 line, its multiresistant variant TA3-MTX-R line and mouse hepatocytes, together with their respective mitochondrial fractions, are described. These derivatives inhibit respiration in both tumour cell lines more effectively than vanillin in the absence or presence of the uncoup...

A clinically useful spectrophotometric method for the determination of 3-methoxy-4hydroxyphenyiglycol (MHPC) is presented. After treatment with barium chloride, the urine is hydrolyzed with Glusulase ($-glucuronidase and sulfatase).f The hydrolysate is passed through a column of Amberlite CG-4Bt to remove any 3methoxy-4-hydroxymandelic acid (MHMA) and the pH is adjusted to neutral. The MHPG is ...

We report the computational and experimental efforts in the design and synthesis of novel neuraminidase (NA) inhibitors from ferulic acid and vanillin. Two proposed ferulic acid analogues, MY7 and MY8 were predicted to inhibit H1N1 NA using molecular docking. From these two analogues, we designed, synthesised and evaluated the biological activities of a series of ferulic acid and vanillin deriv...

Hedonic reactions to various rewards play a key role in various forms of motivated behavior. The influence of repeated experience of social victories or defeats in daily agonistic interactions between male mice on voluntary consumption of vanillin sucrose solution used as hedonic reinforcer was studied. Intake of vanillin sucrose solution was shown to decrease in the winners and losers exposed ...

Synthesis of a novel calix[4]resorcinarene-chitosan hybrid using vanillin as raw material has been conducted. The synthesis was carried out in four steps i.e. (1) allylation of vanillin, (2) HCl-catalyzed condensation allyl vanillin with resorcinol, (3) chloromethylation of C-4-allyloxy-3-methoxyphenylcalix[4] resorcinarene with paraformaldehyde and HCl in the presence of ZnCl 2 to yield tetrak...

In this study, vanillin, a quorum sensing (QS) blocker, and proteinase K were employed to investigate the effect of QS and extracellular proteins on the microbial attachment of aerobic granular activated sludge (AGAS). Results clearly showed that both vanillin and proteinase K could reduce attachment potential of AGAS, and the combined use of them was more effective in reducing attachment bioma...

This paper describes a reversed-phase liquid chromatographic method for the determination of vanillin, associated natural aromatic compounds and/or synthetic precursors, ethyl vanillin, and coumarin, a commonly encountered adulterant in nonbeverage and beverage alcohol products using a ternary gradient mobile phase. The compounds were separated on a Nova-Pak C18 column by using water, methanol,...