Bioprosthetic valve dysfunction represent a serious drawback that limits the wider clinical use of these medical devices for valvular heart disease surgery. Modern studies describe view pathophysiologists on this problem as multifactorial multi-stage process causes irreversible changes in bioprosthesis components, ultimately leading to its dysfunction. However, addition under- standing and mani...

Valvular heart disease is common in patients with end-stage renal disease and, if symptomatic, may lead to valve replacement surgery. However, some patients with renal failure are deemed unsuitable for cardiac surgery, and in those patients who do undergo surgery, there is a significantly greater morbidity and mortality. Transcatheter aortic valve implantation (TAVI) is recognized as an option ...

AIM While the incidence of rheumatic heart disease has declined dramatically over the last half-century, the number of valve surgeries has not changed. This study was undertaken to define the most common type of valvular heart disease requiring surgery today, and determine in-hospital surgical mortality and length-of-stay (LOS) for isolated aortic or mitral valve surgery in a United States tert...

In the era of structural heart disease where catheterbased treatment is prevailing, surgery may have a unique role. For example, surgery may be potentially advantageous in functional mitral regurgitation (FMR), a ventricular disease that not only needs valvular treatment but also requires a ventricular intervention. Being stimulated by the innovative work by Kron et al. (1), we reported anterio...

Background In the context of endemic left-sided rheumatic heart disease, tricuspid valve disease requiring surgical intervention merits closer scrutiny in order to analyse surgical outcomes with presently employed techniques. Aims To evaluate the results of simultaneous tricuspid valve surgery for severe functional tricuspid regurgitation in rheumatic heart disease at the time of left-sided val...

aortic stenosis in patients who cannot undergo surgery. N Engl J Med 2010; 363:1597–1607. 10. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ. Transcatheter versus surgical aorticvalve replacement...

Introduction Infective endocarditis is defined as the infection of the endocardial surface of the heart, which may include one or more heart valves or the mural endocardium. It results in severe valvular insufficiency, which may lead to congestive heart failure, and myocardial abscesses. One of the most feared complications is thromboembolism, through infected emboli. The purpose of this paper ...

a 5-year-old girl was admitted to the hospital with chest pain, fever and dyspnea. physical examination showed normal heart sounds, diminished pulmonary sounds in the left hemithorax and a normal ecg. on chest x-ray the heart was slightly enlarged with moderate left pleural effusion. ct scan revealed pleural effusion and a hypodense mass at the apex of the heart. a cystic mass was detected by e...