Paravalvular leakage (PVL) is uncommon but potentially serious complication after valve replacement, which occurs 7% to 17% after mitral valve replacement (MVR) and 2% to 10% after aortic valve replacement. Although most PVLs are asymptomatic and have a benign clinical course, an estimated 1% to 5% of patients with PVLs show serious clinical consequences, with especially more undesirable outcom...

BACKGROUND The United Kingdom Heart Valve Registry (UKHVR) has recently completed collecting information on 52 659 heart valve replacements (in 47 718 patients) performed during the period 1986 to 1995 in the whole of the United Kingdom. Information stored in the UKHVR's computer database was used for this study. Factors affecting the time from first prosthesis to first redo prosthesis were ana...

OBJECTIVE The aim of this study was to analyze the midterm clinical results of aortic valve replacement with cryopreserved homografts. MATERIALS AND METHODS Aortic valve replacement was performed in 40 patients with cryopreserved homograft. The indications were aortic valve endocarditis in 20 patients (50%), truncus arteriosus in 6 patients (15%), and re-stenosis or regurtitation after aortic...

Since the first cardiac valve replacement in the early sixth decade of the last century, the search continued for ideal cardiac valve substitute with proven structural durability over a period of 10 to 20 years, central flow orifice without transvalvular gradient, absence of host reactivity deleterious to valve function, non-thrombogenecity without the use of anti-coagulant, resistance to infec...

BACKGROUND Minimal data exist on the long-term survival of dialysis patients after cardiac valve surgery. Current practice guidelines of the American College of Cardiology/American Heart Association Task Force on the management of patients with valvular heart disease proscribe the use of bioprosthetic (tissue) valves in hemodialysis patients. METHODS AND RESULTS Dialysis patients hospitalized...

recently, there have been more reports of cardiac valve infections due to the increasing number of intravenous (iv) drug abusers and chronic renal failure patients. among cardiac valves, tricuspid valve is most commonly affected in the course of endocarditis. appropriate management of these patients is a challenging and controversial issue in the field of cardiac surgery. treatment options in s...

IMPORTANCE In nonelderly patients with mitral disease requiring valve replacement, deciding between bioprosthetic and mechanical prosthetic valves is challenging because long-term survival and morbidity are not well defined. OBJECTIVE To quantify survival and major morbidity after mitral valve replacement in patients aged 50 to 69 years. DESIGN, SETTING, AND PARTICIPANTS Retrospective cohor...

Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011, providing a critically needed alternative therapy for patients with severe aortic stenosis previously refused surgical aortic valve replacement (SAVR). Over 20,000 TAVR have been performed in patients worldwide since 2002 when Alain Cribier performed the first-in-man TAVR. This paper reviews the data f...