OBJECTIVES We studied the acute effects of cardiac resynchronization therapy (CRT) on functional mitral regurgitation in heart failure (HF) patients with left bundle branch block (LBBB). BACKGROUND Both an decrease [corrected] in left ventricular (LV) closing force and mitral valve tethering have been implicated as mechanisms for functional mitral regurgitation (FMR) in dilated hearts. We hyp...

The purpose of this study is to determine the optimum intake valve closing time of a large diesel engine having lower fuel consumption and lower NOx emission. The performance simulation has been conducted for this purpose, and a phenomenological combustion model is verified by experimental data of heat release rate and NOx emission in order to enhance the prediction quality of the performance s...

Solenoid valves are a core component of most solution perfusion systems used in neuroscience research. As they open and close, they control the flow of solution through each perfusion line, thereby modulating the timing and sequence of chemical stimulation. The valves feature a ferromagnetic plunger that moves due to the magnetization of the solenoid and returns to its initial position with the...

State-of-the-art tissue engineered heart valves are not strong enough to withstand aortic blood pressure levels. When a strong and slowly degrading scaffold is used, the starting position of valvular tissue engineering is a stronger valve and seeded cells are allowed more time to create a strong extracellular matrix. A polycaprolactone knitted patch with leaflets was developed as a valvular sca...

Heart valve disease (HVD) is a globally increasing problem and accounts for thousands of deaths yearly. Currently end-stage HVD can only be treated by total valve replacement, however with major drawbacks. To overcome the limitations of conventional substitutes, a new clinical approach based on cell colonization of artificially manufactured heart valves has been developed. Even though this atte...

Noninvasive techniques are helpful in evaluating the function of mechanical prostheses and tissue valves. Combined phonocardiography and M-mode echocardiography together with cinefluoroscopy are the most useful noninvasive techniques in differentiating normal from abnormal metallic prosthetic valve function. The intensity of the opening and closing clicks and associated murmurs will depend on t...

Valve sounds are mostly a result of heart valves opening and closing. Laminar blood flow is interrupted abruptly transforms into turbulent flow, causing some sounds, explained by improper valve operation. It has been feasible to demonstrate that the typical compulsive instances different for both chronological spatial aspects through examination phono-cardiographic signals. The current work pre...

To improve the dynamic response speed of high-speed solenoid valves in electric fuel injection systems marine diesel engines, a numerical simulation model valve is described this paper. The accuracy was verified on test bed valve. effect punch position and size were investigated by using distribution law electromagnetic force armature. results showed that armature drilling inter-yoke zone can o...