نتایج جستجو برای: usnic acid

تعداد نتایج: 747448  

Journal: :Separations 2023

Leishmaniasis is considered one of the most untreated tropical diseases in world. In this study, we investigated vitro leishmanicidal activity and cytotoxicity various isolated lichen substances, including atranorin (1), usnic acid (2), gyrophoric (3), salazinic (4), galbinic (5), parietin (6), some semi-synthetic imine derivatives (7, 8, 9) (10, 11, 12, 13). Imine condensation reactions with h...

2012
Margret Bessadottir Mar Egilsson Eydis Einarsdottir Iris H. Magnusdottir Margret H. Ogmundsdottir Sesselja Omarsdottir Helga M. Ogmundsdottir

The lichen compound usnic acid (UA) is a lipophilic weak acid that acts as a proton shuttle and causes loss of mitochondrial inner membrane potential. In the current study we show that UA treatment induced the formation of autophagosomes in human cancer cells, but had minimal effects on normal human fibroblasts. However, autophagic flux was incomplete, degradation of autophagosomal content did ...

Journal: :International Journal of Environmental and Agriculture Research 2017

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