Hepatotoxic effect of (+)usnic acid, the active constituent of Usnea siamensis Wainio was studied in rats, isolated rat hepatocytes and isolated rat liver mitochondria. In rats, after treatment with high dose of (+)usnic acid (200 mg/kg per day, i.p.) for 5 days, there was no significant change in serum transaminase activity (serum AST, ALT) while the electron micrographs showed apparent morpho...

Leishmaniasis is considered by the World Health Organization as one of the infectious parasitic diseases endemic of great relevance and a global public health problem. Pentavalent antimonials used for treatment of this disease are limited and new phytochemicals emerge as an alternative to existing treatments, due to the low toxicity and cost reduction. Usnic acid is uniquely found in lichens an...

Notodiscus hookeri is the only representative of terrestrial gastropods on Possession Island and exclusively feeds on lichens. The known toxicity of various lichen metabolites to plant-eating invertebrates led us to propose that N. hookeri evolved means to protect itself from their adverse effects. To validate this assumption, the current study focused on the consumption of two lichen species: ...

Integrated studies on the interplay between soils, periglacial geomorphology and plant communities are crucial for the understanding of climate change effects on terrestrial ecosystems of maritime Antarctica, one of the most sensitive areas to global warming. Knowledge on physical environmental factors that influence plant communities can greatly benefit studies on the monitoring of climate cha...

Forest canopies modify microclimates and create habitats for nonvascular epiphytes, but we need to better understand the mechanisms regulating their vertical horizontal distributions. Here examine how canopy structure light environment influence 3D distribution of Usnea longissima, world’s longest lichen, associated with old-growth forests. We quantified forest structure, profile (PPFD transmit...

This study was conducted to identify and classify the lichens; determine the diversity index and richness of lichens. A total of 36 species belonging to six genera under three families was identified. Lichen species were mostly found at moderate high altitudinal range with an elevation of 1,131 meters above sea level and open areas where they received adequate sunlight with high moisture and hu...